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Non-Canonical Hedgehog Signaling Is a Positive Regulator of the WNT Pathway and Is Required for the Survival of Colon Cancer Stem Cells.
Regan, Joseph L; Schumacher, Dirk; Staudte, Stephanie; Steffen, Andreas; Haybaeck, Johannes; Keilholz, Ulrich; Schweiger, Caroline; Golob-Schwarzl, Nicole; Mumberg, Dominik; Henderson, David; Lehrach, Hans; Regenbrecht, Christian R A; Schäfer, Reinhold; Lange, Martin.
Afiliación
  • Regan JL; Bayer AG, Drug Discovery, Pharmaceuticals, 13342 Berlin, Germany; Charité Comprehensive Cancer Center, Charité - Universitätsmedizin Berlin, Charitéplatz 1, 10117 Berlin, Germany. Electronic address: joseph.regan@charite.de.
  • Schumacher D; Laboratory of Molecular Tumor Pathology, Charité Universitätsmedizin Berlin, 10117 Berlin, Germany; German Cancer Consortium (DKTK), DKFZ, Im Neuenheimer Feld 280, 69120 Heidelberg, Germany.
  • Staudte S; Bayer AG, Drug Discovery, Pharmaceuticals, 13342 Berlin, Germany; Charité Comprehensive Cancer Center, Charité - Universitätsmedizin Berlin, Charitéplatz 1, 10117 Berlin, Germany.
  • Steffen A; Bayer AG, Drug Discovery, Pharmaceuticals, 13342 Berlin, Germany.
  • Haybaeck J; Department of Pathology, Medical Faculty, Otto von Guericke University Magdeburg, Leipziger Straße 44, Haus 28, 39120 Magdeburg, Germany; Institute of Pathology, Medical University Graz, Auenbruggerplatz 25, 8036 Graz, Austria.
  • Keilholz U; Charité Comprehensive Cancer Center, Charité - Universitätsmedizin Berlin, Charitéplatz 1, 10117 Berlin, Germany.
  • Schweiger C; Institute of Pathology, Medical University Graz, Auenbruggerplatz 25, 8036 Graz, Austria.
  • Golob-Schwarzl N; Institute of Pathology, Medical University Graz, Auenbruggerplatz 25, 8036 Graz, Austria.
  • Mumberg D; Bayer AG, Drug Discovery, Pharmaceuticals, 13342 Berlin, Germany.
  • Henderson D; Bayer AG, Drug Discovery, Pharmaceuticals, 13342 Berlin, Germany.
  • Lehrach H; Max Planck Institute for Molecular Genetics, Ihnestrasse 73, 14195 Berlin, Germany.
  • Regenbrecht CRA; Charité Comprehensive Cancer Center, Charité - Universitätsmedizin Berlin, Charitéplatz 1, 10117 Berlin, Germany; cpo - cellular phenomics & oncology Berlin-Buch GmbH, Robert-Rössle-Straße 10, 13125 Berlin, Germany.
  • Schäfer R; Charité Comprehensive Cancer Center, Charité - Universitätsmedizin Berlin, Charitéplatz 1, 10117 Berlin, Germany; Laboratory of Molecular Tumor Pathology, Charité Universitätsmedizin Berlin, 10117 Berlin, Germany; German Cancer Consortium (DKTK), DKFZ, Im Neuenheimer Feld 280, 69120 Heidelberg, Germ
  • Lange M; Bayer AG, Drug Discovery, Pharmaceuticals, 13342 Berlin, Germany. Electronic address: martin.lange@bayer.com.
Cell Rep ; 21(10): 2813-2828, 2017 Dec 05.
Article en En | MEDLINE | ID: mdl-29212028
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Células Madre Neoplásicas / Neoplasias del Colon / Proteínas Hedgehog Límite: Animals / Female / Humans Idioma: En Revista: Cell Rep Año: 2017 Tipo del documento: Article Pais de publicación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Células Madre Neoplásicas / Neoplasias del Colon / Proteínas Hedgehog Límite: Animals / Female / Humans Idioma: En Revista: Cell Rep Año: 2017 Tipo del documento: Article Pais de publicación: Estados Unidos