Dihydrofisetin exerts its anti-inflammatory effects associated with suppressing ERK/p38 MAPK and Heme Oxygenase-1 activation in lipopolysaccharide-stimulated RAW 264.7 macrophages and carrageenan-induced mice paw edema.

Li, Kai Kai; Shen, Shan Shan; Deng, Xiangyi; Shiu, Hoi Ting; Siu, Wing Sum; Leung, Ping Chung; Ko, Chun Hay; Cheng, Bao Hui

Li, Kai Kai; Shen, Shan Shan; Deng, Xiangyi; Shiu, Hoi Ting; Siu, Wing Sum; Leung, Ping Chung; Ko, Chun Hay; Cheng, Bao Hui.

Afiliación

Li KK; College of Food Science and Technology, Huazhong Agricultural University, Wuhan 430070, China.
Shen SS; Wuhan Children's Hospital (Wuhan Maternal and Child Healthcare Hospital), Tongji Medical College, Huazhong University of Science & Technology.
Deng X; College of Food Science and Technology, Huazhong Agricultural University, Wuhan 430070, China.
Shiu HT; Institute of Chinese Medicine, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong SAR, China.
Siu WS; Institute of Chinese Medicine, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong SAR, China.
Leung PC; Institute of Chinese Medicine, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong SAR, China.
Ko CH; Institute of Chinese Medicine, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong SAR, China. Electronic address: gohey@cuhk.edu.hk.
Cheng BH; Shenzhen Key Laboratory of ENT, Longgang ENT hospital & Institute of ENT, Shenzhen 518172, China. Electronic address: chengbaohui@sina.com.

Int Immunopharmacol ; 54: 366-374, 2018 Jan.

Article en En | MEDLINE | ID: mdl-29202300

Asunto(s)

Antiinflamatorios/farmacología; Edema/tratamiento farmacológico; Flavonoides/farmacología; Macrófagos/inmunología; Animales; Antiinflamatorios/química; Carragenina; Citocinas; Edema/inducido químicamente; Flavonoides/química; Flavonoles; Hemo-Oxigenasa 1/metabolismo; Lipopolisacáridos/inmunología; Proteínas de la Membrana/metabolismo; Ratones; Quinasas de Proteína Quinasa Activadas por Mitógenos/metabolismo; Óxido Nítrico/metabolismo; Células RAW 264.7; Transducción de Señal; Proteínas Quinasas p38 Activadas por Mitógenos/metabolismo

Palabras clave

Anti-inflammation; Dihydrofisetin; HO-1; NF-κB; ROS

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Flavonoides / Edema / Macrófagos / Antiinflamatorios Tipo de estudio: Risk_factors_studies Límite: Animals Idioma: En Revista: Int Immunopharmacol Asunto de la revista: ALERGIA E IMUNOLOGIA / FARMACOLOGIA Año: 2018 Tipo del documento: Article País de afiliación: China Pais de publicación: Países Bajos

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