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Sleep Architecture in Children With Common Phenotype of Obstructive Sleep Apnea.
Durdik, Peter; Sujanska, Anna; Suroviakova, Stanislava; Evangelisti, Melania; Banovcin, Peter; Villa, Maria Pia.
Afiliación
  • Durdik P; Comenius University in Bratislava, Jessenius Faculty of Medicine in Martin, Pediatric Department, Slovakia.
  • Sujanska A; Comenius University in Bratislava, Jessenius Faculty of Medicine in Martin, Pediatric Department, Slovakia.
  • Suroviakova S; Neuroscience, Mental Health and Sense Organs Department, Pediatric Sleep Disease Centre, S. Andrea Hospital, "Sapienza" University of Rome, Rome, Italy.
  • Evangelisti M; Comenius University in Bratislava, Jessenius Faculty of Medicine in Martin, Pediatric Department, Slovakia.
  • Banovcin P; Neuroscience, Mental Health and Sense Organs Department, Pediatric Sleep Disease Centre, S. Andrea Hospital, "Sapienza" University of Rome, Rome, Italy.
  • Villa MP; Comenius University in Bratislava, Jessenius Faculty of Medicine in Martin, Pediatric Department, Slovakia.
J Clin Sleep Med ; 14(1): 9-14, 2018 01 15.
Article en En | MEDLINE | ID: mdl-29198306
STUDY OBJECTIVES: In children, the effect of the common phenotype of obstructive sleep apnea (OSA) on sleep architecture is not adequately documented. The aim of this study was to evaluate sleep architecture in a pediatric population with the common phenotype of OSA. METHODS: The prospective cross-sectional study included 116 children in the age range of 3 to 8 years with suspected OSA and 51 healthy children. All children underwent standard overnight in-laboratory video polysomnography. Patients with obstructive apnea-hypopnea index ≥ 1, adenotonsillar hypertrophy, a long face, narrow palate or minor malocclusions, and no obesity were defined as a common phenotype. Polysomnographic parameters of sleep architecture and sleep clinical record were statistically analyzed according to OSA and its severity. RESULTS: In total, 94 pediatric patients (59.60% male) received the diagnosis of the common phenotype of OSA (mean age of 5.25 ± 1.39 years). A lower percentage of stage N3 sleep (27.70 ± 3.76% versus 31.02 ± 4.23%; P < .05), a greater percentage of stage N1 sleep (8.40 ± 3.98% versus 2.68 ± 3.02%, P < .01), reduced deep sleep efficiency (46.01 ± 4.98% versus 50.25 ± 3.72%; P < .05) and longer sleep latency (18.40 ± 8.48 minutes versus 9.90 ± 11.55 minutes, P < .01) were found in children with the common phenotype of OSA compared with healthy controls. No significant differences were found in total sleep time, sleep efficiency, and percentage of stage R sleep and stage N2 sleep between groups and in sleep stage distribution and cyclization. CONCLUSIONS: These findings suggest that the most common phenotype of pediatric OSA has a negative effect on the structure of sleep, but other clinical studies are needed to confirm this result.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Polisomnografía / Apnea Obstructiva del Sueño Tipo de estudio: Observational_studies / Prevalence_studies / Risk_factors_studies Límite: Child / Child, preschool / Female / Humans / Male Idioma: En Revista: J Clin Sleep Med Año: 2018 Tipo del documento: Article País de afiliación: Eslovaquia Pais de publicación: Estados Unidos

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Polisomnografía / Apnea Obstructiva del Sueño Tipo de estudio: Observational_studies / Prevalence_studies / Risk_factors_studies Límite: Child / Child, preschool / Female / Humans / Male Idioma: En Revista: J Clin Sleep Med Año: 2018 Tipo del documento: Article País de afiliación: Eslovaquia Pais de publicación: Estados Unidos