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Nanoparticle-mediated cryosurgery for tumor therapy.
Hou, Yi; Sun, Ziqiao; Rao, Wei; Liu, Jing.
Afiliación
  • Hou Y; Beijing Key Laboratory of CryoBiomedical Engineering and Key Laboratory of Cryogenics, Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Beijing, PR China; School of Future Technology, University of Chinese Academy of Sciences, Beijing, PR China.
  • Sun Z; Beijing Engineering Research Center of Sustainable Energy and Buildings, Beijing University of Civil Engineering and Architecture, Beijing, PR China.
  • Rao W; Beijing Key Laboratory of CryoBiomedical Engineering and Key Laboratory of Cryogenics, Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Beijing, PR China; School of Future Technology, University of Chinese Academy of Sciences, Beijing, PR China. Electronic address: weirao@m
  • Liu J; Beijing Key Laboratory of CryoBiomedical Engineering and Key Laboratory of Cryogenics, Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Beijing, PR China; School of Future Technology, University of Chinese Academy of Sciences, Beijing, PR China; Department of Biomedical Eng
Nanomedicine ; 14(2): 493-506, 2018 02.
Article en En | MEDLINE | ID: mdl-29197593
Cryosurgery is an energy-based surgical technique. It is minimally invasive and has fewer side effects than surgical resection. However, its insufficient freezing to target tumor and unavoidable injury to healthy tissue have restricted its success. Nano-cryosurgery is the combination of cryogenic biomedicine and nanotechnology. Its principle is to introduce a nanoparticle solution into target tissues to maximize heat transfer, lower the end temperature, increase ice ball formation, and prevent healthy tissues from being frozen. This review covers common nanoplatforms for nano-cryosurgery. The characteristics, advantages, potential challenges, future prospects of applying nano-cryosurgery are discussed in detail.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Criocirugía / Nanopartículas / Congelación / Calor / Modelos Biológicos / Neoplasias Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: Nanomedicine Asunto de la revista: BIOTECNOLOGIA Año: 2018 Tipo del documento: Article Pais de publicación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Criocirugía / Nanopartículas / Congelación / Calor / Modelos Biológicos / Neoplasias Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: Nanomedicine Asunto de la revista: BIOTECNOLOGIA Año: 2018 Tipo del documento: Article Pais de publicación: Estados Unidos