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Does motivation matter in upper-limb rehabilitation after stroke? ArmeoSenso-Reward: study protocol for a randomized controlled trial.
Widmer, Mario; Held, Jeremia P; Wittmann, Frieder; Lambercy, Olivier; Lutz, Kai; Luft, Andreas R.
Afiliación
  • Widmer M; Division of Vascular Neurology and Neurorehabilitation, Department of Neurology, University Hospital of Zurich, Zurich, Switzerland. mario.widmer@cereneo.ch.
  • Held JP; cereneo, Center for Neurology and Rehabilitation, Vitznau, Switzerland. mario.widmer@cereneo.ch.
  • Wittmann F; Neural Control of Movement Laboratory, ETH Zurich, Zurich, Switzerland. mario.widmer@cereneo.ch.
  • Lambercy O; Division of Vascular Neurology and Neurorehabilitation, Department of Neurology, University Hospital of Zurich, Zurich, Switzerland.
  • Lutz K; cereneo, Center for Neurology and Rehabilitation, Vitznau, Switzerland.
  • Luft AR; Rehabilitation Engineering Laboratory, ETH Zurich, Zurich, Switzerland.
Trials ; 18(1): 580, 2017 Dec 02.
Article en En | MEDLINE | ID: mdl-29197412
BACKGROUND: Fifty percent of all stroke survivors remain with functional impairments of their upper limb. While there is a need to improve the effectiveness of rehabilitative training, so far no new training approach has proven to be clearly superior to conventional therapy. As training with rewarding feedback has been shown to improve motor learning in humans, it is hypothesized that rehabilitative arm training could be enhanced by rewarding feedback. In this paper, we propose a trial protocol investigating rewards in the form of performance feedback and monetary gains as ways to improve effectiveness of rehabilitative training. METHODS: This multicentric, assessor-blinded, randomized controlled trial uses the ArmeoSenso virtual reality rehabilitation system to train 74 first-ever stroke patients (< 100 days post stroke) to lift their impaired upper limb against gravity and to improve the workspace of the paretic arm. Three sensors are attached to forearm, upper arm, and trunk to track arm movements in three-dimensional space while controlling for trunk compensation. Whole-arm movements serve as input for a therapy game. The reward group (n = 37) will train with performance feedback and contingent monetary reward. The control group (n = 37) uses the same system but without monetary reward and with reduced performance feedback. Primary outcome is the change in the hand workspace in the transversal plane. Standard clinical assessments are used as secondary outcome measures. DISCUSSION: This randomized controlled trial will be the first to directly evaluate the effect of rewarding feedback, including monetary rewards, on the recovery process of the upper limb following stroke. This could pave the way for novel types of interventions with significantly improved treatment benefits, e.g., for conditions that impair reward processing (stroke, Parkinson's disease). TRIAL REGISTRATION: ClinicalTrials.gov, ID: NCT02257125 . Registered on 30 September 2014.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Recompensa / Accidente Cerebrovascular / Retroalimentación Psicológica / Extremidad Superior / Terapia de Exposición Mediante Realidad Virtual / Rehabilitación de Accidente Cerebrovascular / Motivación / Actividad Motora Tipo de estudio: Clinical_trials / Diagnostic_studies / Guideline Límite: Humans País/Región como asunto: Europa Idioma: En Revista: Trials Asunto de la revista: MEDICINA / TERAPEUTICA Año: 2017 Tipo del documento: Article País de afiliación: Suiza Pais de publicación: Reino Unido

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Recompensa / Accidente Cerebrovascular / Retroalimentación Psicológica / Extremidad Superior / Terapia de Exposición Mediante Realidad Virtual / Rehabilitación de Accidente Cerebrovascular / Motivación / Actividad Motora Tipo de estudio: Clinical_trials / Diagnostic_studies / Guideline Límite: Humans País/Región como asunto: Europa Idioma: En Revista: Trials Asunto de la revista: MEDICINA / TERAPEUTICA Año: 2017 Tipo del documento: Article País de afiliación: Suiza Pais de publicación: Reino Unido