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Improvement of blood lipid profiles by Goishi tea polyphenols in a randomised, double-blind, placebo-controlled clinical study.
Ishida, Nanao; Iizuka, Michiro; Kataoka, Koichi; Okazaki, Masafumi; Shiraishi, Kayo; Yagi, Yusuke; Jobu, Kohei; Yokota, Junko; Oishi, Masao; Moriyama, Hironori; Shimamura, Tomoko; Matsumura, Yoshihisa; Ukeda, Hiroyuki; Miyamura, Mitsuhiko.
Afiliación
  • Ishida N; a Kochi Medical Graduate School , Kochi , Japan.
  • Iizuka M; b Department of Pharmacy , Kochi Medical School Hospital , Kochi , Japan.
  • Kataoka K; b Department of Pharmacy , Kochi Medical School Hospital , Kochi , Japan.
  • Okazaki M; b Department of Pharmacy , Kochi Medical School Hospital , Kochi , Japan.
  • Shiraishi K; b Department of Pharmacy , Kochi Medical School Hospital , Kochi , Japan.
  • Yagi Y; b Department of Pharmacy , Kochi Medical School Hospital , Kochi , Japan.
  • Jobu K; b Department of Pharmacy , Kochi Medical School Hospital , Kochi , Japan.
  • Yokota J; b Department of Pharmacy , Kochi Medical School Hospital , Kochi , Japan.
  • Oishi M; b Department of Pharmacy , Kochi Medical School Hospital , Kochi , Japan.
  • Moriyama H; c Otoyo Town Office , Kochi , Japan.
  • Shimamura T; d Kochi Prefectural Industrial Technology Centre , Kochi , Japan.
  • Matsumura Y; e Faculty of Agriculture and Marine Science , Kochi University , Kochi , Japan.
  • Ukeda H; f Department of Laboratory Medicine , Kochi Medical School , Kochi , Japan.
  • Miyamura M; g Centre for Regional Collaboration (CRC), Kochi University , Kochi , Japan.
Int J Food Sci Nutr ; 69(5): 598-607, 2018 Aug.
Article en En | MEDLINE | ID: mdl-29182039
Dyslipidaemia is a risk factor for arteriosclerosis. Recent studies have shown that dyslipidaemia is effectively prevented by various polyphenols. In this clinical study (UMIN trial: 000024028), we evaluated the beneficial effects of polyphenols contained in Goishi tea on blood lipid profiles. Seventy-seven subjects with LDL cholesterol (CHO) ≧120 mg/mL were randomly divided into two groups for 12 weeks of polyphenol intake as follows: the Goishi tea group for daily consumption of Goishi tea containing 122 mg of polyphenols and the placebo group for the corresponding consumption of a placebo drink containing 12.2 mg of polyphenols. Intake of Goishi tea polyphenols tended to increase HDL CHO and suppress the elevation of triglycerides. These effects were particularly notable among the subjects with a body mass index <25 kg/m2. These findings suggest that Goishi tea polyphenols may suppress arteriosclerosis and reduce cardiovascular event risk by improving blood lipid profiles and thereby preventing dyslipidaemia.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Té / Triglicéridos / Polifenoles / Hiperlipidemias / HDL-Colesterol / LDL-Colesterol Tipo de estudio: Clinical_trials / Risk_factors_studies Límite: Adult / Female / Humans / Male / Middle aged Idioma: En Revista: Int J Food Sci Nutr Asunto de la revista: CIENCIAS DA NUTRICAO Año: 2018 Tipo del documento: Article País de afiliación: Japón Pais de publicación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Té / Triglicéridos / Polifenoles / Hiperlipidemias / HDL-Colesterol / LDL-Colesterol Tipo de estudio: Clinical_trials / Risk_factors_studies Límite: Adult / Female / Humans / Male / Middle aged Idioma: En Revista: Int J Food Sci Nutr Asunto de la revista: CIENCIAS DA NUTRICAO Año: 2018 Tipo del documento: Article País de afiliación: Japón Pais de publicación: Reino Unido