Kudinoside-D, a triterpenoid saponin derived from Ilex kudingcha suppresses adipogenesis through modulation of the AMPK pathway in 3T3-L1 adipocytes.

Che, Yanyun; Wang, Qiuhong; Xiao, Ruyue; Zhang, Jiayu; Zhang, Yaqiong; Gu, Wen; Rao, Gaoxiong; Wang, Changfu; Kuang, Haixue

Che, Yanyun; Wang, Qiuhong; Xiao, Ruyue; Zhang, Jiayu; Zhang, Yaqiong; Gu, Wen; Rao, Gaoxiong; Wang, Changfu; Kuang, Haixue.

Afiliación

Che Y; Engineering Laboratory for National Healthcare Theories and Products of Yunnan Province, College of Pharmaceutical Science, Yunnan University of Traditional Chinese Medicine, No. 1076 Yuhua Road, Chenggong District, Kunming 650500, Yunnan, China.
Wang Q; Guangdong Pharmaceutical University, Guangzhou 510006, China. Electronic address: qhwang668@sina.com.
Xiao R; Heilongjiang University of Chinese Medicine, No. 24 Heping Road, Harbin 150040, China.
Zhang J; Center of Scientific experiment, Beijing University of Chinese Medicine, Beijing 10029, China.
Zhang Y; Engineering Laboratory for National Healthcare Theories and Products of Yunnan Province, College of Pharmaceutical Science, Yunnan University of Traditional Chinese Medicine, No. 1076 Yuhua Road, Chenggong District, Kunming 650500, Yunnan, China.
Gu W; Engineering Laboratory for National Healthcare Theories and Products of Yunnan Province, College of Pharmaceutical Science, Yunnan University of Traditional Chinese Medicine, No. 1076 Yuhua Road, Chenggong District, Kunming 650500, Yunnan, China.
Rao G; Engineering Laboratory for National Healthcare Theories and Products of Yunnan Province, College of Pharmaceutical Science, Yunnan University of Traditional Chinese Medicine, No. 1076 Yuhua Road, Chenggong District, Kunming 650500, Yunnan, China.
Wang C; Guangdong Pharmaceutical University, Guangzhou 510006, China.
Kuang H; Heilongjiang University of Chinese Medicine, No. 24 Heping Road, Harbin 150040, China. Electronic address: hxkuang56@163.com.

Fitoterapia ; 125: 208-216, 2018 Mar.

Article en En | MEDLINE | ID: mdl-29170122

Asunto(s)

Proteínas Quinasas Activadas por AMP/metabolismo; Adipocitos/efectos de los fármacos; Adipogénesis/efectos de los fármacos; Ilex/química; Saponinas/farmacología; Triterpenos/farmacología; Células 3T3-L1; Animales; Fármacos Antiobesidad/farmacología; Proteína alfa Potenciadora de Unión a CCAAT/metabolismo; Ratones; PPAR gamma/metabolismo; Fosforilación; Transducción de Señal/efectos de los fármacos; Proteína 1 de Unión a los Elementos Reguladores de Esteroles/metabolismo

Palabras clave

3T3-L1 preadipocytes; AMP-activated protein kinase (AMPK); Anti-adipogenic activity; Anti-obesity; Ilex Kudingcha; Kudinoside-D

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Saponinas / Triterpenos / Adipocitos / Ilex / Adipogénesis / Proteínas Quinasas Activadas por AMP Límite: Animals Idioma: En Revista: Fitoterapia Año: 2018 Tipo del documento: Article País de afiliación: China Pais de publicación: Países Bajos

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