Diterpenoid Alkaloids from Two Aconitum Species with Antifeedant Activity against Spodoptera exigua.
J Nat Prod
; 80(12): 3136-3142, 2017 12 22.
Article
en En
| MEDLINE
| ID: mdl-29154542
Twenty-five diterpenoid alkaloids were isolated from the roots of two Aconitum species. The structures of seven new C19-diterpenoid alkaloids, apetaldines A-G (1-7), and 10 known alkaloids (8-17) from Aconitum apetalum and eight known alkaloids (18-25) from Aconitum franchetii var. villosulum were elucidated via HRESIMS, IR, and NMR data. Alkaloids 1-10, 15, 16, and 18-25 were screened for their antifeedant activity. Among the compounds tested, chasmanthinine (19) showed highly potent antifeedant activity with an effective concentration for 50% feeding reduction (EC50) at 0.07 mg/cm2. The antifeedant structure-activity relationship of the diterpenoid alkaloids is also discussed.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Spodoptera
/
Aconitum
/
Diterpenos
/
Alcaloides
Límite:
Animals
Idioma:
En
Revista:
J Nat Prod
Año:
2017
Tipo del documento:
Article
Pais de publicación:
Estados Unidos