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Associations between tumor necrosis factor-α gene polymorphisms and the risk of Guillain-Barré syndrome and its subtypes: A systematic review and meta-analysis.
Liu, Ju; Lian, Zhiyun; Chen, Hongxi; Shi, Ziyan; Feng, Huiru; Du, Qin; Zhang, Qin; Zhou, Hongyu.
Afiliación
  • Liu J; Department of Neurology, West China Hospital, Sichuan University, Guo Xuexiang #37, Chengdu 610041, China.
  • Lian Z; Department of Neurology, West China Hospital, Sichuan University, Guo Xuexiang #37, Chengdu 610041, China.
  • Chen H; Department of Neurology, West China Hospital, Sichuan University, Guo Xuexiang #37, Chengdu 610041, China.
  • Shi Z; Department of Neurology, West China Hospital, Sichuan University, Guo Xuexiang #37, Chengdu 610041, China.
  • Feng H; Department of Neurology, West China Hospital, Sichuan University, Guo Xuexiang #37, Chengdu 610041, China.
  • Du Q; Department of Neurology, West China Hospital, Sichuan University, Guo Xuexiang #37, Chengdu 610041, China.
  • Zhang Q; Department of Neurology, West China Hospital, Sichuan University, Guo Xuexiang #37, Chengdu 610041, China.
  • Zhou H; Department of Neurology, West China Hospital, Sichuan University, Guo Xuexiang #37, Chengdu 610041, China. Electronic address: zhouhy@scu.edu.cn.
J Neuroimmunol ; 313: 25-33, 2017 12 15.
Article en En | MEDLINE | ID: mdl-29153605
This meta-analysis aimed to assess the relationship between tumor necrosis factor-α (TNF-α) polymorphisms and Guillain-Barré syndrome (GBS) or its subtypes of acute inflammatory demyelinating polyneuropathy (AIDP), acute motor axonal neuropathy (AMAN), and acute motor-sensory axonal neuropathy (AMSAN). A total of six studies with 1013 cases and 1029 controls were included. Our pooled data indicated that TNF-α 308G/A polymorphism was significantly associated with GBS, AMAN, and AMSAN but not with AIDP; TNF-α 857C/T polymorphism was significantly associated with AMAN but not with GBS or AIDP. Besides, no association was found between TNF-α 238G/A and 863C/A polymorphisms and GBS or its subtypes.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Factor de Necrosis Tumoral alfa / Síndrome de Guillain-Barré / Polimorfismo de Nucleótido Simple Tipo de estudio: Etiology_studies / Risk_factors_studies / Systematic_reviews Límite: Humans Idioma: En Revista: J Neuroimmunol Año: 2017 Tipo del documento: Article País de afiliación: China Pais de publicación: Países Bajos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Factor de Necrosis Tumoral alfa / Síndrome de Guillain-Barré / Polimorfismo de Nucleótido Simple Tipo de estudio: Etiology_studies / Risk_factors_studies / Systematic_reviews Límite: Humans Idioma: En Revista: J Neuroimmunol Año: 2017 Tipo del documento: Article País de afiliación: China Pais de publicación: Países Bajos