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Advances in microfluidic devices made from thermoplastics used in cell biology and analyses.
Gencturk, Elif; Mutlu, Senol; Ulgen, Kutlu O.
Afiliación
  • Gencturk E; Department of Chemical Engineering, Biosystems Engineering Laboratory, Bogazici University, 34342 Istanbul, Turkey.
  • Mutlu S; Department of Electrical and Electronics Engineering, BUMEMS Laboratory, Bogazici University, 34342 Istanbul, Turkey.
  • Ulgen KO; Department of Chemical Engineering, Biosystems Engineering Laboratory, Bogazici University, 34342 Istanbul, Turkey.
Biomicrofluidics ; 11(5): 051502, 2017 Sep.
Article en En | MEDLINE | ID: mdl-29152025
Silicon and glass were the main fabrication materials of microfluidic devices, however, plastics are on the rise in the past few years. Thermoplastic materials have recently been used to fabricate microfluidic platforms to perform experiments on cellular studies or environmental monitoring, with low cost disposable devices. This review describes the present state of the development and applications of microfluidic systems used in cell biology and analyses since the year 2000. Cultivation, separation/isolation, detection and analysis, and reaction studies are extensively discussed, considering only microorganisms (bacteria, yeast, fungi, zebra fish, etc.) and mammalian cell related studies in the microfluidic platforms. The advantages/disadvantages, fabrication methods, dimensions, and the purpose of creating the desired system are explained in detail. An important conclusion of this review is that these microfluidic platforms are still open for research and development, and solutions need to be found for each case separately.

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Biomicrofluidics Año: 2017 Tipo del documento: Article País de afiliación: Turquía Pais de publicación: Estados Unidos

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Biomicrofluidics Año: 2017 Tipo del documento: Article País de afiliación: Turquía Pais de publicación: Estados Unidos