Biomarker identification for statin sensitivity of cancer cell lines.

Raghu, Vineet K; Beckwitt, Colin H; Warita, Katsuhiko; Wells, Alan; Benos, Panayiotis V; Oltvai, Zoltán N

Raghu, Vineet K; Beckwitt, Colin H; Warita, Katsuhiko; Wells, Alan; Benos, Panayiotis V; Oltvai, Zoltán N.

Afiliación

Raghu VK; Department of Computational & Systems Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15260, USA; Department of Computer Science, University of Pittsburgh, Pittsburgh, PA 15213, USA.
Beckwitt CH; Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA.
Warita K; Department of Veterinary Anatomy, School of Veterinary Medicine, Tottori University, Tottori 680-8553, Japan.
Wells A; Department of Computational & Systems Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15260, USA; Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA; University of Pittsburgh Cancer Institute, Pittsburgh, PA 15213, USA.
Benos PV; Department of Computational & Systems Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15260, USA; Department of Computer Science, University of Pittsburgh, Pittsburgh, PA 15213, USA. Electronic address: benos@pitt.edu.
Oltvai ZN; Department of Computational & Systems Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15260, USA; Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA. Electronic address: oltvai@pitt.edu.

Biochem Biophys Res Commun ; 495(1): 659-665, 2018 01 01.

Article en En | MEDLINE | ID: mdl-29146185

Asunto(s)

Antineoplásicos/uso terapéutico; Biomarcadores de Tumor/metabolismo; Descubrimiento de Drogas/métodos; Ensayos de Selección de Medicamentos Antitumorales/métodos; Inhibidores de Hidroximetilglutaril-CoA Reductasas/metabolismo; Neoplasias/tratamiento farmacológico; Neoplasias/metabolismo; Línea Celular Tumoral; Bases de Datos de Proteínas; Relación Dosis-Respuesta a Droga; Humanos; Neoplasias/patología; Resultado del Tratamiento

Palabras clave

Biomarkers; Graphical models; Statin

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Ensayos de Selección de Medicamentos Antitumorales / Biomarcadores de Tumor / Inhibidores de Hidroximetilglutaril-CoA Reductasas / Descubrimiento de Drogas / Neoplasias / Antineoplásicos Tipo de estudio: Diagnostic_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Humans Idioma: En Revista: Biochem Biophys Res Commun Año: 2018 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos

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