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Human stem cell-derived astrocytes replicate human prions in a PRNP genotype-dependent manner.
Krejciova, Zuzana; Alibhai, James; Zhao, Chen; Krencik, Robert; Rzechorzek, Nina M; Ullian, Erik M; Manson, Jean; Ironside, James W; Head, Mark W; Chandran, Siddharthan.
Afiliación
  • Krejciova Z; National CJD Research & Surveillance Unit, Centre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, Scotland, UK.
  • Alibhai J; Institute for Neurodegenerative Diseases, University of California, San Francisco, San Francisco, CA.
  • Zhao C; National CJD Research & Surveillance Unit, Centre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, Scotland, UK.
  • Krencik R; Medical Research Council Centre for Regenerative Medicine, University of Edinburgh, Edinburgh, Scotland, UK.
  • Rzechorzek NM; Department of Neurosurgery, Center for Neuroregeneration, Houston Methodist Research Institute, Houston, TX.
  • Ullian EM; Medical Research Council Centre for Regenerative Medicine, University of Edinburgh, Edinburgh, Scotland, UK.
  • Manson J; Royal (Dick) School of Veterinary Studies and The Roslin Institute, University of Edinburgh, Edinburgh, Scotland, UK.
  • Ironside JW; Department of Ophthalmology, University of California, San Francisco, San Francisco, CA.
  • Head MW; Neurobiology Division, The Roslin Institute, University of Edinburgh, Edinburgh, Scotland, UK.
  • Chandran S; National CJD Research & Surveillance Unit, Centre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, Scotland, UK.
J Exp Med ; 214(12): 3481-3495, 2017 Dec 04.
Article en En | MEDLINE | ID: mdl-29141869
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Priones / Astrocitos / Células Madre Pluripotentes Inducidas / Proteínas Priónicas Límite: Adult / Female / Humans / Male / Middle aged Idioma: En Revista: J Exp Med Año: 2017 Tipo del documento: Article País de afiliación: Reino Unido Pais de publicación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Priones / Astrocitos / Células Madre Pluripotentes Inducidas / Proteínas Priónicas Límite: Adult / Female / Humans / Male / Middle aged Idioma: En Revista: J Exp Med Año: 2017 Tipo del documento: Article País de afiliación: Reino Unido Pais de publicación: Estados Unidos