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Design, synthesis and biological evaluation of novel benzimidazole amidines as potent multi-target inhibitors for the treatment of non-small cell lung cancer.
Bistrovic, Andrea; Krstulovic, Luka; Harej, Anja; Grbcic, Petra; Sedic, Mirela; Kostrun, Sanja; Pavelic, Sandra Kraljevic; Bajic, Miroslav; Raic-Malic, Silvana.
Afiliación
  • Bistrovic A; Department of Organic Chemistry, Faculty of Chemical Engineering and Technology, University of Zagreb, Marulicev Trg 20, HR-10000 Zagreb, Croatia.
  • Krstulovic L; Department of Chemistry and Biochemistry, Faculty of Veterinary Medicine, University of Zagreb, Heinzelova 55, HR-10000 Zagreb, Croatia.
  • Harej A; Department of Biotechnology, Center for High-Throughput Technologies, University of Rijeka, Ulica Radmile Matejcic 2, HR-51000 Rijeka, Croatia.
  • Grbcic P; Department of Biotechnology, Center for High-Throughput Technologies, University of Rijeka, Ulica Radmile Matejcic 2, HR-51000 Rijeka, Croatia.
  • Sedic M; Department of Biotechnology, Center for High-Throughput Technologies, University of Rijeka, Ulica Radmile Matejcic 2, HR-51000 Rijeka, Croatia.
  • Kostrun S; Chemistry Department, Fidelta Ltd., Prilaz Baruna Filipovica 29, HR-10000 Zagreb, Croatia.
  • Pavelic SK; Department of Biotechnology, Center for High-Throughput Technologies, University of Rijeka, Ulica Radmile Matejcic 2, HR-51000 Rijeka, Croatia.
  • Bajic M; Department of Chemistry and Biochemistry, Faculty of Veterinary Medicine, University of Zagreb, Heinzelova 55, HR-10000 Zagreb, Croatia.
  • Raic-Malic S; Department of Organic Chemistry, Faculty of Chemical Engineering and Technology, University of Zagreb, Marulicev Trg 20, HR-10000 Zagreb, Croatia. Electronic address: sraic@fkit.hr.
Eur J Med Chem ; 143: 1616-1634, 2018 Jan 01.
Article en En | MEDLINE | ID: mdl-29133046
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Bencimidazoles / Diseño de Fármacos / Carcinoma de Pulmón de Células no Pequeñas / Inhibidores de Proteínas Quinasas / Amidinas / Neoplasias Pulmonares / Antineoplásicos Límite: Humans Idioma: En Revista: Eur J Med Chem Año: 2018 Tipo del documento: Article País de afiliación: Croacia Pais de publicación: Francia
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Bencimidazoles / Diseño de Fármacos / Carcinoma de Pulmón de Células no Pequeñas / Inhibidores de Proteínas Quinasas / Amidinas / Neoplasias Pulmonares / Antineoplásicos Límite: Humans Idioma: En Revista: Eur J Med Chem Año: 2018 Tipo del documento: Article País de afiliación: Croacia Pais de publicación: Francia