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Missing pieces of the puzzle to effectively control digital dermatitis.
Orsel, K; Plummer, P; Shearer, J; De Buck, J; Carter, S D; Guatteo, R; Barkema, H W.
Afiliación
  • Orsel K; Department of Production Animal Health, Faculty of Veterinary Medicine, University of Calgary, Calgary, AB, Canada.
  • Plummer P; Department of Veterinary Diagnostic and Production Animal Medicine, Iowa State University College of Veterinary Medicine, Ames, IA, USA.
  • Shearer J; Department of Veterinary Microbiology and Preventative Medicine, Iowa State University College of Veterinary Medicine, Ames, IA, USA.
  • De Buck J; Department of Veterinary Microbiology and Preventative Medicine, Iowa State University College of Veterinary Medicine, Ames, IA, USA.
  • Carter SD; Department of Production Animal Health, Faculty of Veterinary Medicine, University of Calgary, Calgary, AB, Canada.
  • Guatteo R; Department of Infection Biology, Institute of Veterinary Science, University of Liverpool, Liverpool, UK.
  • Barkema HW; BIOEPAR, INRA, Oniris, Nantes, France.
Transbound Emerg Dis ; 65 Suppl 1: 186-198, 2018 May.
Article en En | MEDLINE | ID: mdl-29124910
Since the first report of bovine digital dermatitis (DD) in 1974, there is a large body of the literature published; however, effective prevention and control of the disease remain elusive. Although many aspects of the pathogenesis of DD have been investigated, even some of the most basic questions such as the aetiology of this disease remain under debate. Treponema spp. have been strongly associated with DD lesions and occur in abundance in advanced lesions; however, efforts to induce disease with pure cultures of these organisms have been largely underwhelming and inconsistent. Furthermore, although the disease has been presented for several decades, there is limited scientific evidence regarding effective treatment of DD. Apparent discrepancies between effectiveness in vitro and in vivo have challenged the scientific community to identify new potential treatment options. With no treatment resulting in a 100% cure rate, the current expectation is manageable control, but prospects for the eradication of the disease are unlikely using current approaches. In order to develop more effective approaches to control DD on-farm, there is a critical need for a deeper understanding regarding the causation, ecology, transmission and treatment of this disease. In this article, we attempt to provide insights into specific research needs related to DD in order to assist the industry, researchers, pharmaceutical companies and research sponsors with decision-making and identified research gaps.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Infecciones por Treponema / Enfermedades de los Bovinos / Dermatitis Digital Límite: Animals Idioma: En Revista: Transbound Emerg Dis Asunto de la revista: MEDICINA VETERINARIA Año: 2018 Tipo del documento: Article País de afiliación: Canadá Pais de publicación: Alemania
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Infecciones por Treponema / Enfermedades de los Bovinos / Dermatitis Digital Límite: Animals Idioma: En Revista: Transbound Emerg Dis Asunto de la revista: MEDICINA VETERINARIA Año: 2018 Tipo del documento: Article País de afiliación: Canadá Pais de publicación: Alemania