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Chronic oxidative stress promotes GADD34-mediated phosphorylation of the TAR DNA-binding protein TDP-43, a modification linked to neurodegeneration.
Goh, Catherine Wenhui; Lee, Irene Chengjie; Sundaram, Jeyapriya Rajameenakshi; George, Simi Elizabeth; Yusoff, Permeen; Brush, Matthew Hayden; Sze, Newman Siu Kwan; Shenolikar, Shirish.
Afiliación
  • Goh CW; Signature Research Programs in Neuroscience and Behavioural Disorders, Singapore 169857, Singapore.
  • Lee IC; Signature Research Programs in Neuroscience and Behavioural Disorders, Singapore 169857, Singapore; Cardiovascular and Metabolic Disorders, Duke-NUS Medical School, Singapore 169857, Singapore.
  • Sundaram JR; Signature Research Programs in Neuroscience and Behavioural Disorders, Singapore 169857, Singapore; Cardiovascular and Metabolic Disorders, Duke-NUS Medical School, Singapore 169857, Singapore.
  • George SE; Cardiovascular and Metabolic Disorders, Duke-NUS Medical School, Singapore 169857, Singapore.
  • Yusoff P; Signature Research Programs in Neuroscience and Behavioural Disorders, Singapore 169857, Singapore; Cardiovascular and Metabolic Disorders, Duke-NUS Medical School, Singapore 169857, Singapore.
  • Brush MH; Ontology Development group, Oregon Health and Science University, Portland, Oregon 97239.
  • Sze NSK; School of Biological Sciences, Nanyang Technological University, Singapore 639798, Singapore.
  • Shenolikar S; Signature Research Programs in Neuroscience and Behavioural Disorders, Singapore 169857, Singapore; Cardiovascular and Metabolic Disorders, Duke-NUS Medical School, Singapore 169857, Singapore; Department of Psychiatry and Behavioral Sciences and Department of Pharmacology and Cancer Biology, Duke U
J Biol Chem ; 293(1): 163-176, 2018 01 05.
Article en En | MEDLINE | ID: mdl-29109149
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Estrés Oxidativo / Proteínas de Unión al ADN / Proteína Fosfatasa 1 / Proteinopatías TDP-43 Límite: Animals / Humans Idioma: En Revista: J Biol Chem Año: 2018 Tipo del documento: Article País de afiliación: Singapur Pais de publicación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Estrés Oxidativo / Proteínas de Unión al ADN / Proteína Fosfatasa 1 / Proteinopatías TDP-43 Límite: Animals / Humans Idioma: En Revista: J Biol Chem Año: 2018 Tipo del documento: Article País de afiliación: Singapur Pais de publicación: Estados Unidos