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The cost-effectiveness of predonation screening for transfusion transmissible infections using rapid test kits in a hospital-based blood transfusion centre.
Dosunmu, Adedoyin Owolabi; Akinbami, Akinsegun Abduljaleel; Ismail, Ayobami Kamal; Olaiya, Modupe Adebimpe; Uche, Ebele Ifeyinwa; Aile, Igbinoba Kingsley.
Afiliación
  • Dosunmu AO; Department of Haematology and Blood Transfusion, Lagos State University Teaching Hospital, Ikeja, Nigeria.
  • Akinbami AA; Department of Haematology and Blood Transfusion, Lagos State University Teaching Hospital, Ikeja, Nigeria.
  • Ismail AK; Department of Haematology and Blood Transfusion, Lagos State University Teaching Hospital, Ikeja, Nigeria.
  • Olaiya MA; Lagos State Blood Transfusion Committee, Lagos Island Maternity Hospital, Lagos, Nigeria.
  • Uche EI; Department of Haematology and Blood Transfusion, Lagos State University Teaching Hospital, Ikeja, Nigeria.
  • Aile IK; Department of Haematology and Blood Transfusion, Lagos State University Teaching Hospital, Ikeja, Nigeria.
Niger Postgrad Med J ; 24(3): 162-167, 2017.
Article en En | MEDLINE | ID: mdl-29082905
OBJECTIVE: Blood transfusion practice emphasises safety, efficacy and appropriate use. These require cost-effective programme management. This study focused on the cost of screening for transfusion transmissible infections (TTI). METHODS: This was a 1 year (2016) analysis of screening in a hospital-based transfusion centre. The cost of screening all blood donors by ELISA was compared to the cost of serial screening starting from rapid kit, taking into account, the estimated cost of blood bags prevented from discard after ELISA screening (attributable cost). The cost of voluntary donor drive plus cost of ELISA screening was compared with the present cost of screening. RESULTS: A total of 5591 donors were screened for HIV, hepatitis B and C using the rapid kit, 291 donors were deferred (5.2%). A total of 5300 units were further screened by ELISA. A total of 435 blood units (8.2%) were discarded due to TTI positivity. TTI positivity rate was 12.98%. Only 2.36% were voluntary donors and among these 9.1% were TTI positive. The attributable cost of serial screening was 55,653.5 USD while that of screening by ELISA only was 55,910 USD. The attributable cost of rapid screening for only hepatitis B and then ELISA was 53,313.9 USD taking into consideration that 187 blood units would be prevented from undue discard. CONCLUSIONS: This analysis demonstrated that with proper donor selection, rapid screening for hepatitis B virus only before ELISA screening is more cost-effective. This will also reduce the waiting time for donors and counselling if HIV positive.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Bancos de Sangre / Donantes de Sangre / Transfusión Sanguínea / Tamizaje Masivo / Análisis Costo-Beneficio / Seguridad de la Sangre Tipo de estudio: Diagnostic_studies / Health_economic_evaluation / Screening_studies Límite: Humans País/Región como asunto: Africa Idioma: En Revista: Niger Postgrad Med J Asunto de la revista: MEDICINA Año: 2017 Tipo del documento: Article País de afiliación: Nigeria Pais de publicación: Nigeria
Texto completo
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XML
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Bancos de Sangre / Donantes de Sangre / Transfusión Sanguínea / Tamizaje Masivo / Análisis Costo-Beneficio / Seguridad de la Sangre Tipo de estudio: Diagnostic_studies / Health_economic_evaluation / Screening_studies Límite: Humans País/Región como asunto: Africa Idioma: En Revista: Niger Postgrad Med J Asunto de la revista: MEDICINA Año: 2017 Tipo del documento: Article País de afiliación: Nigeria Pais de publicación: Nigeria