Your browser doesn't support javascript.
loading
Ustekinumab Drug Levels in Maternal and Cord Blood in a Woman With Crohn's Disease Treated Until 33 Weeks of Gestation.
Rowan, Catherine R; Cullen, Garret; Mulcahy, Hugh E; Keegan, Denise; Byrne, Kathryn; Murphy, Deirdre J; Sheridan, Juliette; Doherty, Glen A.
Afiliación
  • Rowan CR; Centre for Colorectal Disease, St Vincent's University Hospital and School of Medicine, University College Dublin, Dublin, Ireland.
  • Cullen G; Centre for Colorectal Disease, St Vincent's University Hospital and School of Medicine, University College Dublin, Dublin, Ireland.
  • Mulcahy HE; Centre for Colorectal Disease, St Vincent's University Hospital and School of Medicine, University College Dublin, Dublin, Ireland.
  • Keegan D; Centre for Colorectal Disease, St Vincent's University Hospital and School of Medicine, University College Dublin, Dublin, Ireland.
  • Byrne K; Centre for Colorectal Disease, St Vincent's University Hospital and School of Medicine, University College Dublin, Dublin, Ireland.
  • Murphy DJ; Academic Department of Obstetrics and Gynaecology, Coombe Women and Infants University Hospital and Trinity College, University of Dublin, Dublin, Ireland.
  • Sheridan J; Centre for Colorectal Disease, St Vincent's University Hospital and School of Medicine, University College Dublin, Dublin, Ireland.
  • Doherty GA; Centre for Colorectal Disease, St Vincent's University Hospital and School of Medicine, University College Dublin, Dublin, Ireland.
J Crohns Colitis ; 12(3): 376-378, 2018 Feb 28.
Article en En | MEDLINE | ID: mdl-29045603
A 35-year old woman with ileocolonic, perianal, and vulval Crohn's disease was treated with subcutaneous ustekinuamb [USK] throughout pregnancy. Dose intervals were shortened from 6-weekly to 4-weekly to maintain clinical remission. The last dose of USK was administered at 33 weeks of gestation, and a healthy baby boy was delivered by caesarean section at 37 weeks. Maternal trough USK levels remained stable during pregnancy. Cord blood USK levels were nearly 2-fold higher than contemporaneous maternal serum levels. To our knowledge, this is the first report of maternal and cord USK levels in a patient with Crohn's disease.
Asunto(s)
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Complicaciones del Embarazo / Fármacos Gastrointestinales / Enfermedad de Crohn / Sangre Fetal / Ustekinumab Límite: Adult / Female / Humans / Male / Newborn / Pregnancy Idioma: En Revista: J Crohns Colitis Asunto de la revista: GASTROENTEROLOGIA Año: 2018 Tipo del documento: Article País de afiliación: Irlanda Pais de publicación: Reino Unido
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Complicaciones del Embarazo / Fármacos Gastrointestinales / Enfermedad de Crohn / Sangre Fetal / Ustekinumab Límite: Adult / Female / Humans / Male / Newborn / Pregnancy Idioma: En Revista: J Crohns Colitis Asunto de la revista: GASTROENTEROLOGIA Año: 2018 Tipo del documento: Article País de afiliación: Irlanda Pais de publicación: Reino Unido