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Increased detection of precancerous cervical lesions with adjunctive dynamic spectral imaging.
DeNardis, Sara A; Lavin, Philip T; Livingston, Jeff; Salter, William R; James-Patrick, Nanette; Papagiannakis, Emmanouil; Olson, Christopher G; Weinberg, Lori.
Afiliación
  • DeNardis SA; Department of Obstetrics/Gynecology, University of Central Florida, Orlando, FL, USA.
  • Lavin PT; Boston Biostatistics Research Foundation, Framingham, MA, USA.
  • Livingston J; MacArthur OB/GYN, Irving, TX, USA.
  • Salter WR; Advanced ObGyn Associates, Richardson, TX, USA.
  • James-Patrick N; Southwest Women's Healthcare Associates, Olympia Fields, IL, USA.
  • Papagiannakis E; DYSIS Medical, Edinburgh, UK.
  • Olson CG; Women's Center for Health, Naperville, IL, USA.
  • Weinberg L; Department of Obstetrics/Gynecology, Advocate Illinois Masonic Medical Center, Chicago, IL, USA.
Int J Womens Health ; 9: 717-725, 2017.
Article en En | MEDLINE | ID: mdl-29033612
OBJECTIVE: To validate, in US community-based colposcopy clinics, previous reports of increased detection of high-grade cervical intraepithelial neoplasia (CIN2+) with biopsies selected using dynamic spectral imaging (DSI) mapping after standard colposcopy. STUDY DESIGN: Cross-sectional observational study of 26 colposcopists across nine clinics recruiting consecutive colposcopy patients. Standard assessment with biopsy selections was completed before seeing the DSI map which was subsequently interpreted and used for additional biopsies per clinical judgment. Primary measure was the number of women with CIN2+ detected by DSI-assisted biopsies, over those detected by standard colposcopy biopsies. RESULTS: A total of 887 women were recruited. After exclusions, 881 women and 1,189 biopsies were analyzed. Standard biopsy detected 78 women with CIN2+ and DSI-assisted biopsies another 34, increasing the detection rate from 8.85% to 12.71% (p=0.00016). This was achieved with 16.16% of DSI-assisted biopsies finding CIN2+ compared to 13.24% for the preceding standard biopsies. For secondary specificity analysis, 431 women had only
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Diagnostic_studies / Observational_studies Idioma: En Revista: Int J Womens Health Año: 2017 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Nueva Zelanda
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Diagnostic_studies / Observational_studies Idioma: En Revista: Int J Womens Health Año: 2017 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Nueva Zelanda