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Age at menarche and depressive symptoms in older Southern Chinese women: A Mendelian randomization study in the Guangzhou Biobank Cohort Study.
Au Yeung, Shiu Lun; Jiang, Chaoqiang; Cheng, Kar Keung; Xu, Lin; Zhang, Weisen; Lam, Tai Hing; Leung, Gabriel Matthew; Schooling, C Mary.
Afiliación
  • Au Yeung SL; School of Public Health, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China.
  • Jiang C; Guangzhou Number 12 Hospital, Guangzhou, China.
  • Cheng KK; Department of Public Health and Epidemiology, University of Birmingham, UK.
  • Xu L; School of Public Health, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China.
  • Zhang W; Guangzhou Number 12 Hospital, Guangzhou, China.
  • Lam TH; School of Public Health, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China; Guangzhou Number 12 Hospital, Guangzhou, China. Electronic address: hrmrlth@hku.hk.
  • Leung GM; School of Public Health, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China.
  • Schooling CM; School of Public Health, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China; City University of New York, Graduate School of Public Health and Health Policy, New York, NY, USA.
Psychiatry Res ; 259: 32-35, 2018 01.
Article en En | MEDLINE | ID: mdl-29028521
To clarify the causal role of age at menarche in depressive symptoms we conducted a Mendelian randomization study using a large Southern Chinese cohort (n = 12,233). A genetic allele score was derived using stepwise regression with cross validation. Older age at menarche was not associated with geriatric depression scale score. Our findings suggest that higher rates of depression in women are likely attributable to other factors which require investigation.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Menarquia / Factores de Edad / Pueblo Asiatico / Depresión Tipo de estudio: Clinical_trials / Diagnostic_studies / Etiology_studies / Incidence_studies / Observational_studies / Risk_factors_studies Límite: Aged / Aged80 / Female / Humans / Male / Middle aged País/Región como asunto: Asia Idioma: En Revista: Psychiatry Res Año: 2018 Tipo del documento: Article País de afiliación: China Pais de publicación: Irlanda
Texto completo
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Imprimir
XML
PubMed Links
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Menarquia / Factores de Edad / Pueblo Asiatico / Depresión Tipo de estudio: Clinical_trials / Diagnostic_studies / Etiology_studies / Incidence_studies / Observational_studies / Risk_factors_studies Límite: Aged / Aged80 / Female / Humans / Male / Middle aged País/Región como asunto: Asia Idioma: En Revista: Psychiatry Res Año: 2018 Tipo del documento: Article País de afiliación: China Pais de publicación: Irlanda