The deubiquitinase UCHL5/UCH37 positively regulates Hedgehog signaling by deubiquitinating Smoothened.

Zhou, Zizhang; Yao, Xia; Pang, Shu; Chen, Ping; Jiang, Weirong; Shan, Zhaoliang; Zhang, Qing

Zhou, Zizhang; Yao, Xia; Pang, Shu; Chen, Ping; Jiang, Weirong; Shan, Zhaoliang; Zhang, Qing.

Afiliación

Zhou Z; State Key Laboratory of Pharmaceutical Biotechnology and MOE Key Laboratory of Model Animals for Disease Study, Model Animal Research Center of Nanjing University, Nanjing, China.
Yao X; Collaborative Innovation Center of Genetics and Development, Shanghai, China.
Pang S; State Key Laboratory of Pharmaceutical Biotechnology and MOE Key Laboratory of Model Animals for Disease Study, Model Animal Research Center of Nanjing University, Nanjing, China.
Chen P; Collaborative Innovation Center of Genetics and Development, Shanghai, China.
Jiang W; State Key Laboratory of Pharmaceutical Biotechnology and MOE Key Laboratory of Model Animals for Disease Study, Model Animal Research Center of Nanjing University, Nanjing, China.
Shan Z; Collaborative Innovation Center of Genetics and Development, Shanghai, China.
Zhang Q; State Key Laboratory of Pharmaceutical Biotechnology and MOE Key Laboratory of Model Animals for Disease Study, Model Animal Research Center of Nanjing University, Nanjing, China.

J Mol Cell Biol ; 10(3): 243-257, 2018 06 01.

Article en En | MEDLINE | ID: mdl-28992318

Asunto(s)

Proteínas de Drosophila/metabolismo; Drosophila/metabolismo; Proteínas Hedgehog/metabolismo; Transducción de Señal; Receptor Smoothened/metabolismo; Ubiquitina Tiolesterasa/metabolismo; Animales; Drosophila/genética; Proteínas de Drosophila/genética; Técnicas de Silenciamiento del Gen; Unión Proteica; Estabilidad Proteica; Ubiquitina Tiolesterasa/genética; Proteasas Ubiquitina-Específicas/metabolismo; Ubiquitinación

Texto completo

Añadir a Mi BVS

Imprimir

XML

PubMed Links

Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Transducción de Señal / Proteínas de Drosophila / Ubiquitina Tiolesterasa / Drosophila / Proteínas Hedgehog / Receptor Smoothened Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: J Mol Cell Biol Asunto de la revista: BIOLOGIA MOLECULAR Año: 2018 Tipo del documento: Article País de afiliación: China Pais de publicación: Estados Unidos

Texto completo

Añadir a Mi BVS

Imprimir

XML

PubMed Links

Buscar en Google