[Therapeutic utilization of stem cells in orthopedics]. / Therapeutische Anwendung von Stammzellen in der Orthopädie.
Orthopade
; 46(12): 1077-1090, 2017 Dec.
Article
en De
| MEDLINE
| ID: mdl-28986619
Stem cells are becoming increasingly more important in the field of regenerative medicine. Adult mesenchymal stem cells (MSCs) are harvested predominantly from bone marrow or adipose tissue, are already being used in the clinical setting and have a low potential for side effects. In orthopedics, experience has been gained in the treatment of bone defects, non-unions, cartilage defects, osteoarthritis and tendon pathologies. The current data are derived from case studies and randomized controlled trials are missing; therefore, there are many open questions concerning the optimal cell source, number of cells, administration technique (e.g. injections and matrices) or combinations with growth factors; however, it is evident from the data that MSCs have a positive effect on tissue regeneration and are safe to use.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Procedimientos Ortopédicos
/
Trasplante de Células Madre Mesenquimatosas
Tipo de estudio:
Clinical_trials
Límite:
Humans
Idioma:
De
Revista:
Orthopade
Año:
2017
Tipo del documento:
Article
Pais de publicación:
Alemania