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Resistance to pyridine-based inhibitor KF116 reveals an unexpected role of integrase in HIV-1 Gag-Pol polyprotein proteolytic processing.
Hoyte, Ashley C; Jamin, Augusta V; Koneru, Pratibha C; Kobe, Matthew J; Larue, Ross C; Fuchs, James R; Engelman, Alan N; Kvaratskhelia, Mamuka.
Afiliación
  • Hoyte AC; From the Center for Retrovirus Research and.
  • Jamin AV; Division of Infectious Diseases, University of Colorado School of Medicine, Aurora, Colorado 80045, and.
  • Koneru PC; Department of Cancer Immunology and Virology, Dana-Farber Cancer Institute and Department of Medicine, Harvard Medical School, Boston, Massachusetts 02215.
  • Kobe MJ; From the Center for Retrovirus Research and.
  • Larue RC; Division of Infectious Diseases, University of Colorado School of Medicine, Aurora, Colorado 80045, and.
  • Fuchs JR; From the Center for Retrovirus Research and.
  • Engelman AN; From the Center for Retrovirus Research and.
  • Kvaratskhelia M; Division of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, The Ohio State University, Columbus, Ohio 43210.
J Biol Chem ; 292(48): 19814-19825, 2017 12 01.
Article en En | MEDLINE | ID: mdl-28972144
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Piridinas / Productos del Gen gag / Productos del Gen pol / VIH-1 / Inhibidores de Integrasa VIH / Integrasa de VIH Límite: Humans Idioma: En Revista: J Biol Chem Año: 2017 Tipo del documento: Article Pais de publicación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Piridinas / Productos del Gen gag / Productos del Gen pol / VIH-1 / Inhibidores de Integrasa VIH / Integrasa de VIH Límite: Humans Idioma: En Revista: J Biol Chem Año: 2017 Tipo del documento: Article Pais de publicación: Estados Unidos