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Trends in utilization and costs of BRCA testing among women aged 18-64 years in the United States, 2003-2014.
Chen, Zhuo; Kolor, Katherine; Grosse, Scott D; Rodriguez, Juan L; Lynch, Julie A; Green, Ridgely Fisk; Dotson, W David; Bowen, M Scott; Khoury, Muin J.
Afiliación
  • Chen Z; Office of Public Health Genomics; Center for Surveillance, Epidemiology and Laboratory Services, Centers for Disease Control and Prevention (CDC), Atlanta, Georgia, USA.
  • Kolor K; Department of Health Policy and Management, College of Public Health, University of Georgia, Athens, Georgia, USA.
  • Grosse SD; School of Economics, University of Nottingham, Ningbo, China.
  • Rodriguez JL; Office of Public Health Genomics; Center for Surveillance, Epidemiology and Laboratory Services, Centers for Disease Control and Prevention (CDC), Atlanta, Georgia, USA.
  • Lynch JA; National Center on Birth Defects and Developmental Disabilities, CDC, Atlanta, Georgia, USA.
  • Green RF; Division of Cancer Prevention and Control, National Center for Chronic Disease Prevention and Health Promotion, CDC, Atlanta, Georgia, USA.
  • Dotson WD; US Department of Veterans Affairs, Salt Lake City Healthcare System, Salt Lake City, Utah, USA.
  • Bowen MS; RTI International, Waltham, Massachusetts, USA.
  • Khoury MJ; Office of Public Health Genomics; Center for Surveillance, Epidemiology and Laboratory Services, Centers for Disease Control and Prevention (CDC), Atlanta, Georgia, USA.
Genet Med ; 20(4): 428-434, 2018 Apr.
Article en En | MEDLINE | ID: mdl-28933789
PurposeWe examined 12-year trends in BRCA testing rates and costs in the context of clinical guidelines, national policies, and other factors.MethodsWe estimated trends in BRCA testing rates and costs from 2003 to 2014 for women aged 18-64 years using private claims data and publicly reported revenues from the primary BRCA testing provider.ResultsThe percentage of women with zero out-of-pocket payments for BRCA testing increased during 2013-2014, after 7 years of general decline, coinciding with a clarification of Affordable Care Act coverage of BRCA genetic testing. Beginning in 2007, family history accounted for an increasing proportion of women with BRCA tests compared with personal history, coinciding with BRCA testing guidelines for primary care settings and direct-to-consumer advertising campaigns. During 2013-2014, BRCA testing rates based on claims grew at a faster rate than revenues, following 3 years of similar growth, consistent with increased marketplace competition. In 2013, BRCA testing rates based on claims increased 57%, compared with 11% average annual increases over the preceding 3 years, coinciding with celebrity publicity.ConclusionThe observed trends in BRCA testing rates and costs are consistent with possible effects of several factors, including the Affordable Care Act, clinical guidelines and celebrity publicity.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Costos Directos de Servicios / Aceptación de la Atención de Salud / Pruebas Genéticas / Genes BRCA1 / Genes BRCA2 Tipo de estudio: Diagnostic_studies / Guideline / Health_economic_evaluation / Prognostic_studies Límite: Adolescent / Adult / Female / Humans / Middle aged País/Región como asunto: America do norte Idioma: En Revista: Genet Med Asunto de la revista: GENETICA MEDICA Año: 2018 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Costos Directos de Servicios / Aceptación de la Atención de Salud / Pruebas Genéticas / Genes BRCA1 / Genes BRCA2 Tipo de estudio: Diagnostic_studies / Guideline / Health_economic_evaluation / Prognostic_studies Límite: Adolescent / Adult / Female / Humans / Middle aged País/Región como asunto: America do norte Idioma: En Revista: Genet Med Asunto de la revista: GENETICA MEDICA Año: 2018 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos