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T Wave Safety Margin during the Process of ICD Implantation As a Novel Predictor of T Wave Oversensing.
Sun, Ya-Xun; Gao, Jing; Jiang, Chen-Yang; Xue, Yu-Mei; Xu, Yi-Zhou; Liu, Gang; Guo, Ji-Hong; Sheng, Xia; Ye, Yang; He, Hong; Zhao, Yun-Tao; Barajas-Martinez, Hector; Fu, Guo-Sheng; Hu, Dan.
Afiliación
  • Sun YX; Department of Cardiology, Sir Run Run Shaw Hospital, Zhejiang University School of MedicineHangzhou, China.
  • Gao J; Department of Cardiology, Sir Run Run Shaw Hospital, Zhejiang University School of MedicineHangzhou, China.
  • Jiang CY; Department of Cardiology, Sir Run Run Shaw Hospital, Zhejiang University School of MedicineHangzhou, China.
  • Xue YM; Department of Cardiology, Guangdong Cardiovascular Institute, Guangdong General HospitalGuangzhou, China.
  • Xu YZ; Department of Cardiology, Hangzhou First People's HospitalHangzhou, China.
  • Liu G; Department of Cardiology, First Hospital of Hebei Medical UniversityShijiazhuang, China.
  • Guo JH; Division of Cardiology, Peking University People's HospitalBeijing, China.
  • Sheng X; Department of Cardiology, Sir Run Run Shaw Hospital, Zhejiang University School of MedicineHangzhou, China.
  • Ye Y; Department of Cardiology, Sir Run Run Shaw Hospital, Zhejiang University School of MedicineHangzhou, China.
  • He H; Department of Cardiology, Sir Run Run Shaw Hospital, Zhejiang University School of MedicineHangzhou, China.
  • Zhao YT; Department of Cardiology, Aerospace Center HospitalBeijing, China.
  • Barajas-Martinez H; Masonic Medical Research LaboratoryUtica, NY, United States.
  • Fu GS; Department of Cardiology, Sir Run Run Shaw Hospital, Zhejiang University School of MedicineHangzhou, China.
  • Hu D; Masonic Medical Research LaboratoryUtica, NY, United States.
Front Physiol ; 8: 659, 2017.
Article en En | MEDLINE | ID: mdl-28919866
Introduction: T wave oversensing (TWOS) is a major drawback of implantable cardioverter defibrillator (ICD) and data on predictors of TWOS in ICD is limited. We aimed to calculate a novel index of T wave safety margin (TWSM) and assess its potential for evaluating TWOS during the procedure of ICD implantation. Methods and Results: Thirty-two consecutive patients with ICD implantation were enrolled. During each procedure of ICD implantation, different ICD generators were connected to implanted sensing lead through active-fixation leads and bridging cables. R and T wave amplitudes were measured on ICD printouts according to the gain. The ICDs were programed to the most sensitive settings to reveal possible TWOS. A novel index TWSM was calculated according to the corresponding sensing algorithm of ICD. There was discrepancy of R wave amplitudes measured by different ICDs (P < 0.01). In Fortify and Teligen ICDs, T wave amplitudes showed no difference (P > 0.05) and TWSMs were sufficiently high (post sensing: 13.0 ± 7.6 and 28.3 ± 16.5, respectively, post pacing: 5.0 ± 2.2 and 4.6 ± 0.9, respectively). In nine patients with 10 TWOS episodes detected during the procedure of ICD implantation, generators with the highest TWSM were chosen. Only one TWOS episode during pacing was recorded during the 25 ± 7 mo follow-up period. Conclusions: We first propose the index of TWSM during ICD implantation as a potentially efficient predictor for TWOS. Evaluation of TWSM might help to reduce TWOS episodes in patients with high risk of TWOS. Prospective studies are warranted to validate this index and its potential to reduce TWOS episodes.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Observational_studies / Prognostic_studies / Risk_factors_studies Idioma: En Revista: Front Physiol Año: 2017 Tipo del documento: Article País de afiliación: China Pais de publicación: Suiza

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Observational_studies / Prognostic_studies / Risk_factors_studies Idioma: En Revista: Front Physiol Año: 2017 Tipo del documento: Article País de afiliación: China Pais de publicación: Suiza