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Safety, pharmacokinetics, and pharmacodynamics of oral omaveloxolone (RTA 408), a synthetic triterpenoid, in a first-in-human trial of patients with advanced solid tumors.
Creelan, Ben C; Gabrilovich, Dmitry I; Gray, Jhanelle E; Williams, Charles C; Tanvetyanon, Tawee; Haura, Eric B; Weber, Jeffrey S; Gibney, Geoffrey T; Markowitz, Joseph; Proksch, Joel W; Reisman, Scott A; McKee, Mark D; Chin, Melanie P; Meyer, Colin J; Antonia, Scott J.
Afiliación
  • Creelan BC; Department of Thoracic Oncology, H. Lee Moffitt Cancer Center and Research Institute, Magnolia Drive, Tampa, FL, USA.
  • Gabrilovich DI; The Wistar Institute, Philadelphia, PA, USA.
  • Gray JE; Department of Thoracic Oncology, H. Lee Moffitt Cancer Center and Research Institute, Magnolia Drive, Tampa, FL, USA.
  • Williams CC; Department of Thoracic Oncology, H. Lee Moffitt Cancer Center and Research Institute, Magnolia Drive, Tampa, FL, USA.
  • Tanvetyanon T; Department of Thoracic Oncology, H. Lee Moffitt Cancer Center and Research Institute, Magnolia Drive, Tampa, FL, USA.
  • Haura EB; Department of Thoracic Oncology, H. Lee Moffitt Cancer Center and Research Institute, Magnolia Drive, Tampa, FL, USA.
  • Weber JS; Laura and Isaac Perlmutter Cancer Center, New York, NY, USA.
  • Gibney GT; Department of Medicine, Georgetown-Lombardi Comprehensive Cancer Center, Washington, DC, USA.
  • Markowitz J; Department of Cutaneous Oncology, H. Lee Moffitt Cancer Center and Research Institute, Magnolia Drive, Tampa, FL, USA.
  • Proksch JW; Reata Pharmaceuticals, Inc., Irving, TX, USA.
  • Reisman SA; Reata Pharmaceuticals, Inc., Irving, TX, USA.
  • McKee MD; AbbVie, Inc., North Chicago, IL, USA.
  • Chin MP; Reata Pharmaceuticals, Inc., Irving, TX, USA.
  • Meyer CJ; Reata Pharmaceuticals, Inc., Irving, TX, USA.
  • Antonia SJ; Department of Thoracic Oncology, H. Lee Moffitt Cancer Center and Research Institute, Magnolia Drive, Tampa, FL, USA.
Onco Targets Ther ; 10: 4239-4250, 2017.
Article en En | MEDLINE | ID: mdl-28919776

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Onco Targets Ther Año: 2017 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Nueva Zelanda

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Onco Targets Ther Año: 2017 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Nueva Zelanda