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Review on Synthetic Chemistry and Antibacterial Importance of Thiazole Derivatives.
Kashyap, Ankita; Adhikari, Nayana; Das, Arpita; Shakya, Anshul; Ghosh, Surajit Kumar; Singh, Udaya Pratap; Bhat, Hans Raj.
Afiliación
  • Kashyap A; Department of Pharmaceutical Sciences, School of Science and Engineering, Dibrugarh University, Dibrugarh - 786 004, Assam, India.
  • Adhikari N; Department of Pharmaceutical Sciences, School of Science and Engineering, Dibrugarh University, Dibrugarh - 786 004, Assam, India.
  • Das A; Department of Pharmaceutical Sciences, School of Science and Engineering, Dibrugarh University, Dibrugarh - 786 004, Assam, India.
  • Shakya A; Department of Pharmaceutical Sciences, School of Science and Engineering, Dibrugarh University, Dibrugarh - 786 004, Assam, India.
  • Ghosh SK; Department of Pharmaceutical Sciences, School of Science and Engineering, Dibrugarh University, Dibrugarh - 786 004, Assam, India.
  • Singh UP; Drug Design & Discovery Laboratory, Department of Pharmaceutical Sciences, Sam Higginbottom University of Agriculture, Technology & Science, Allahabad 211007, India.
  • Bhat HR; Department of Pharmaceutical Sciences, School of Science and Engineering, Dibrugarh University, Dibrugarh - 786 004, Assam, India.
Curr Drug Discov Technol ; 15(3): 214-228, 2018.
Article en En | MEDLINE | ID: mdl-28901248
BACKGROUND: Thiazole is one of the leading heterocyclic five-member ring compounds that contain nitrogen and sulphur atom. Many natural and/or synthetic compounds contain thiazole as an essential moiety and possess diverse therapeutic activities. The thiazole ring was modified at different positions to generate new molecules with potent antibacterial activities. Thus, the present review enumerates the antibacterial importance of thiazole and its derivatives. METHOD: The mining of literature has been performed using different database which includes only peer-reviewed journals. The quality of retrieved papers was appraised using standard tools. Moreover, the significant papers were described in detail to focus on thiazole derivatives showing considerable antibacterial activity. RESULT: The present review describes the chemistry, SAR (Structure Activity Relationship) studies and antibacterial importance of thiazole with different synthetic procedures. CONCLUSION: This particular study certainly benefits the researchers interested in exploiting the antibacterial activity of thiazoles in search of novel agents.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Tiazoles / Antibacterianos Límite: Humans Idioma: En Revista: Curr Drug Discov Technol Asunto de la revista: FARMACOLOGIA Año: 2018 Tipo del documento: Article País de afiliación: India Pais de publicación: Emiratos Árabes Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Tiazoles / Antibacterianos Límite: Humans Idioma: En Revista: Curr Drug Discov Technol Asunto de la revista: FARMACOLOGIA Año: 2018 Tipo del documento: Article País de afiliación: India Pais de publicación: Emiratos Árabes Unidos