Resistance of a measles virus mutant to fusion inhibitory oligopeptides is not associated with mutations in the fusion peptide.
Virology
; 159(2): 368-72, 1987 Aug.
Article
en En
| MEDLINE
| ID: mdl-2887065
The nucleotide sequence and predicted amino acid sequence has been obtained for the fusion (F) protein gene of the R93 strain of measles virus and compared to that of the parental strain, Edmonston B. The R93 strain is a mutant measles virus which is able to grow and induce cell fusion in the presence of the fusion inhibiting oligopeptide, Z-D-Phe-L-Phe-L-(NO2)Arg (SV4814). Primer extension sequencing on isolated R93 mRNA demonstrated the presence of three nucleotide changes leading to three amino acid changes, none of which are in the hydrophobic NH2-terminal region of the F1 polypeptide.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Proteínas Virales de Fusión
/
Virus del Sarampión
Tipo de estudio:
Risk_factors_studies
Límite:
Animals
Idioma:
En
Revista:
Virology
Año:
1987
Tipo del documento:
Article
Pais de publicación:
Estados Unidos