Your browser doesn't support javascript.
loading
Spontaneous regression of anterior mediastinal seminoma with normalization of ß-human chorionic gonadotropin levels.
Yu, Zaiqiang; Kimura, Daisuke; Tsushima, Takao; Fukuda, Ikuo.
Afiliación
  • Yu Z; Department of Thoracic and Cardiovascular Surgery, Hirosaki University Graduate School of Medicine, Aomori, Japan.
  • Kimura D; Department of Thoracic and Cardiovascular Surgery, Hirosaki University Graduate School of Medicine, Aomori, Japan.
  • Tsushima T; Department of Thoracic and Cardiovascular Surgery, Hirosaki University Graduate School of Medicine, Aomori, Japan.
  • Fukuda I; Department of Thoracic and Cardiovascular Surgery, Hirosaki University Graduate School of Medicine, Aomori, Japan. Electronic address: ikuofuku@hirosaki-u.ac.jp.
Int J Surg Case Rep ; 39: 199-202, 2017.
Article en En | MEDLINE | ID: mdl-28854409
INTRODUCTION: Although spontaneous regression (SR) of anterior mediastinal seminoma is very rare with normalization of ß-human chorionic gonadotropin (ß-hCG) level, video-assisted thoracic surgery (VATS) is the most effective solution for definite diagnosis of indeterminate anterior mediastinal masses. DIAGNOSIS, THERAPEUTIC INTERVENTIONS, AND OUTCOMES: A rare case of an asymptomatic 37-year-old man with an anterior mediastinal mass that was detected on a routine chest X-ray is presented. Computed tomography (CT) showed a large anterior mediastinal tumor with superior vena cava invasion and SR before VATS for definitive diagnosis. On pathology, the definitive diagnosis was seminoma. Microscopic examination showed abundant apoptotic cells within the tumor. Chemotherapy (bleomycin 30mg/day, etoposide 200mg/day, cisplatin 40mg/day) was given to this patient, and the tumor showed high sensitivity. CONCLUSION: Anterior mediastinal seminoma showing SR induced by spontaneous apoptosis of tumor cells may have good sensitivity to chemotherapy, and a good clinical outcome may be achieved in these patients. This case also highlights that VATS is the most effective solution for definite diagnosis of indeterminate anterior mediastinal masses.
Palabras clave
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Int J Surg Case Rep Año: 2017 Tipo del documento: Article País de afiliación: Japón Pais de publicación: Países Bajos
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Int J Surg Case Rep Año: 2017 Tipo del documento: Article País de afiliación: Japón Pais de publicación: Países Bajos