Transcriptional induction of cellular gene expression during lytic infection with herpes simplex virus.
Biosci Rep
; 6(11): 945-51, 1986 Nov.
Article
en En
| MEDLINE
| ID: mdl-2883998
Herpes simplex virus Type 2 causes a severe repression of host cell biosynthesis at a number of levels. We show that despite this, non-viral cDNA clones derived from cellular RNA species which accumulate to high levels after infection can be isolated using differential screening techniques. By using nuclear run-off assays, we have shown that this RNA accumulation is mediated by transcriptional induction of the corresponding cellular genes.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Poli A
/
Transcripción Genética
/
ARN Mensajero
/
Regulación de la Expresión Génica
/
Simplexvirus
Límite:
Animals
Idioma:
En
Revista:
Biosci Rep
Año:
1986
Tipo del documento:
Article
Pais de publicación:
Reino Unido