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Neural breathing pattern in newborn infants pre- and postextubation.
Iyer, Narayan P; Dickson, John; Ruiz, Michelle E; Chatburn, Robert; Beck, Jennifer; Sinderby, Chister; Rodriguez, Ricardo J.
Afiliación
  • Iyer NP; Department of Neonatology, Cleveland Clinic Children's Hospital, Cleveland, OH, USA.
  • Dickson J; Department of Neonatology, Cleveland Clinic Children's Hospital, Cleveland, OH, USA.
  • Ruiz ME; Department of Neonatology, Cleveland Clinic Children's Hospital, Cleveland, OH, USA.
  • Chatburn R; Department of Neonatology, Cleveland Clinic Children's Hospital, Cleveland, OH, USA.
  • Beck J; Department of Critical Care, Keenan Research Centre for Biomedical Science of St. Michael's Hospital, Toronto, ON, Canada.
  • Sinderby C; Department of Pediatrics, University of Toronto, Toronto, ON, Canada.
  • Rodriguez RJ; Department of Critical Care, Keenan Research Centre for Biomedical Science of St. Michael's Hospital, Toronto, ON, Canada.
Acta Paediatr ; 106(12): 1928-1933, 2017 Dec.
Article en En | MEDLINE | ID: mdl-28833570
AIM: To describe the neural breathing pattern before and after extubation in newborn infants. METHODS: Prospective, observational study. In infants deemed ready for extubation, the diaphragm electrical activity (EAdi) was continuously recorded from 30 minute before to two hours after extubation. RESULTS: Total of 25 neonates underwent 29 extubations; 10 extubations resulted in re-intubation within 72 hours. Postextubation, there was an increase in peak EAdi (EAdi-max) and EAdi-delta (peak minus minimum EAdi) in both groups. The pre- to postextubation change in EAdi-max (8.9-11.1 µv) and EAdi-delta (6-8 µv) was less in the failure group in comparison with the change in EAdi-max (10.2-13.4 µv) and EAdi-delta (6.3-10.6 µv) in the success group, (p = 0.02 and 0.01, respectively). CONCLUSION: In our neonatal cohort, extubation failure was associated with a smaller increase in peak and delta EAdi after extubation. If confirmed, these findings indicate an important cause of extubation failure in preterm infants.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Respiración / Diafragma / Extubación Traqueal Tipo de estudio: Observational_studies / Risk_factors_studies Límite: Female / Humans / Male / Newborn Idioma: En Revista: Acta Paediatr Año: 2017 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Noruega

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Respiración / Diafragma / Extubación Traqueal Tipo de estudio: Observational_studies / Risk_factors_studies Límite: Female / Humans / Male / Newborn Idioma: En Revista: Acta Paediatr Año: 2017 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Noruega