Cell-mediated immunity to a synthetic gliadin peptide resembling a sequence from adenovirus 12.
Lancet
; 1(8538): 884-6, 1987 Apr 18.
Article
en En
| MEDLINE
| ID: mdl-2882290
Cell-mediated immunity to a synthetic peptide, which has a 12-residue sequence from A-gliadin analogous to part of an early-region protein (Elb) from adenovirus 12, was investigated in patients with coeliac disease, healthy subjects, and disease controls by means of an indirect leucocyte-migration-inhibition assay. Patients with coeliac disease being treated with a gluten-free diet showed a significantly greater response than healthy subjects (p less than 0.001) or patients with inflammatory bowel disease. This cellular immune response was dependent on antigen concentration and was not present in untreated coeliac patients.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Fragmentos de Péptidos
/
Proteínas de Plantas
/
Enfermedad Celíaca
/
Proteínas Oncogénicas Virales
/
Gliadina
/
Leucocitos
Límite:
Adult
/
Aged
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
En
Revista:
Lancet
Año:
1987
Tipo del documento:
Article
Pais de publicación:
Reino Unido