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Discovery and process development of a novel TACE inhibitor for the topical treatment of psoriasis.
Boiteau, Jean-Guy; Ouvry, Gilles; Arlabosse, Jean-Marie; Astri, Stéphanie; Beillard, Audrey; Bhurruth-Alcor, Yushma; Bonnary, Laetitia; Bouix-Peter, Claire; Bouquet, Karine; Bourotte, Marilyne; Cardinaud, Isabelle; Comino, Catherine; Deprez, Benoît; Duvert, Denis; Féret, Angélique; Hacini-Rachinel, Feriel; Harris, Craig S; Luzy, Anne-Pascale; Mathieu, Arnaud; Millois, Corinne; Orsini, Nicolas; Pascau, Jonathan; Pinto, Artur; Piwnica, David; Polge, Gaëlle; Reitz, Arnaud; Reversé, Kevin; Rodeville, Nicolas; Rossio, Patricia; Spiesse, Delphine; Tabet, Samuel; Taquet, Nathalie; Tomas, Loïc; Vial, Emmanuel; Hennequin, Laurent F.
Afiliación
  • Boiteau JG; Nestlé Skin Health R&D, Les Templiers 2400 Route des Colles, 06410 Biot, France. Electronic address: jean-guy.boiteau@galderma.com.
  • Ouvry G; Nestlé Skin Health R&D, Les Templiers 2400 Route des Colles, 06410 Biot, France. Electronic address: gilles.ouvry@galderma.com.
  • Arlabosse JM; Nestlé Skin Health R&D, Les Templiers 2400 Route des Colles, 06410 Biot, France.
  • Astri S; Nestlé Skin Health R&D, Les Templiers 2400 Route des Colles, 06410 Biot, France.
  • Beillard A; Nestlé Skin Health R&D, Les Templiers 2400 Route des Colles, 06410 Biot, France.
  • Bhurruth-Alcor Y; Nestlé Skin Health R&D, Les Templiers 2400 Route des Colles, 06410 Biot, France.
  • Bonnary L; Nestlé Skin Health R&D, Les Templiers 2400 Route des Colles, 06410 Biot, France.
  • Bouix-Peter C; Nestlé Skin Health R&D, Les Templiers 2400 Route des Colles, 06410 Biot, France.
  • Bouquet K; Nestlé Skin Health R&D, Les Templiers 2400 Route des Colles, 06410 Biot, France.
  • Bourotte M; Univ. Lille, Inserm, Institut Pasteur de Lille, U1177 - Drugs and Molecules for Living Systems, F-59000 Lille, France.
  • Cardinaud I; Nestlé Skin Health R&D, Les Templiers 2400 Route des Colles, 06410 Biot, France.
  • Comino C; Nestlé Skin Health R&D, Les Templiers 2400 Route des Colles, 06410 Biot, France.
  • Deprez B; Univ. Lille, Inserm, Institut Pasteur de Lille, U1177 - Drugs and Molecules for Living Systems, F-59000 Lille, France.
  • Duvert D; Nestlé Skin Health R&D, Les Templiers 2400 Route des Colles, 06410 Biot, France.
  • Féret A; Nestlé Skin Health R&D, Les Templiers 2400 Route des Colles, 06410 Biot, France.
  • Hacini-Rachinel F; Nestlé Skin Health R&D, Les Templiers 2400 Route des Colles, 06410 Biot, France.
  • Harris CS; Nestlé Skin Health R&D, Les Templiers 2400 Route des Colles, 06410 Biot, France.
  • Luzy AP; Nestlé Skin Health R&D, Les Templiers 2400 Route des Colles, 06410 Biot, France.
  • Mathieu A; Univ. Lille, Inserm, Institut Pasteur de Lille, U1177 - Drugs and Molecules for Living Systems, F-59000 Lille, France.
  • Millois C; Nestlé Skin Health R&D, Les Templiers 2400 Route des Colles, 06410 Biot, France.
  • Orsini N; Nestlé Skin Health R&D, Les Templiers 2400 Route des Colles, 06410 Biot, France.
  • Pascau J; Nestlé Skin Health R&D, Les Templiers 2400 Route des Colles, 06410 Biot, France.
  • Pinto A; Univ. Lille, Inserm, Institut Pasteur de Lille, U1177 - Drugs and Molecules for Living Systems, F-59000 Lille, France.
  • Piwnica D; Nestlé Skin Health R&D, Les Templiers 2400 Route des Colles, 06410 Biot, France.
  • Polge G; Nestlé Skin Health R&D, Les Templiers 2400 Route des Colles, 06410 Biot, France.
  • Reitz A; Nestlé Skin Health R&D, Les Templiers 2400 Route des Colles, 06410 Biot, France.
  • Reversé K; Nestlé Skin Health R&D, Les Templiers 2400 Route des Colles, 06410 Biot, France.
  • Rodeville N; Nestlé Skin Health R&D, Les Templiers 2400 Route des Colles, 06410 Biot, France.
  • Rossio P; Nestlé Skin Health R&D, Les Templiers 2400 Route des Colles, 06410 Biot, France.
  • Spiesse D; Nestlé Skin Health R&D, Les Templiers 2400 Route des Colles, 06410 Biot, France.
  • Tabet S; Nestlé Skin Health R&D, Les Templiers 2400 Route des Colles, 06410 Biot, France.
  • Taquet N; Nestlé Skin Health R&D, Les Templiers 2400 Route des Colles, 06410 Biot, France.
  • Tomas L; Nestlé Skin Health R&D, Les Templiers 2400 Route des Colles, 06410 Biot, France.
  • Vial E; Nestlé Skin Health R&D, Les Templiers 2400 Route des Colles, 06410 Biot, France.
  • Hennequin LF; Nestlé Skin Health R&D, Les Templiers 2400 Route des Colles, 06410 Biot, France.
Bioorg Med Chem ; 26(4): 945-956, 2018 02 15.
Article en En | MEDLINE | ID: mdl-28818461
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Inhibidores Enzimáticos / Proteína ADAM17 Tipo de estudio: Prognostic_studies Límite: Animals / Female / Humans Idioma: En Revista: Bioorg Med Chem Asunto de la revista: BIOQUIMICA / QUIMICA Año: 2018 Tipo del documento: Article Pais de publicación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Inhibidores Enzimáticos / Proteína ADAM17 Tipo de estudio: Prognostic_studies Límite: Animals / Female / Humans Idioma: En Revista: Bioorg Med Chem Asunto de la revista: BIOQUIMICA / QUIMICA Año: 2018 Tipo del documento: Article Pais de publicación: Reino Unido