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Comparative effects of plant oils and trans-fat on blood lipid profiles and ischemic stroke in rats.
Guo, Haiyu; Ban, Young-Hwan; Cha, Yeseul; Kim, Tae-Su; Lee, Sung-Pyo; Suk An, Eun; Choi, Jieun; Woom Seo, Da; Yon, Jung-Min; Choi, Ehn-Kyoung; Kim, Yun-Bae.
Afiliación
  • Guo H; Veterinary Medical Center and College of Veterinary Medicine, Chungbuk National University, Cheongju, Chungbuk, Republic of Korea.
  • Ban YH; Veterinary Medical Center and College of Veterinary Medicine, Chungbuk National University, Cheongju, Chungbuk, Republic of Korea.
  • Cha Y; Veterinary Medical Center and College of Veterinary Medicine, Chungbuk National University, Cheongju, Chungbuk, Republic of Korea.
  • Kim TS; Anydoctor Healthcare Co., Ltd., Cheonan, Chungnam, Republic of Korea.
  • Lee SP; Anydoctor Healthcare Co., Ltd., Cheonan, Chungnam, Republic of Korea.
  • Suk An E; Veterinary Medical Center and College of Veterinary Medicine, Chungbuk National University, Cheongju, Chungbuk, Republic of Korea.
  • Choi J; Veterinary Medical Center and College of Veterinary Medicine, Chungbuk National University, Cheongju, Chungbuk, Republic of Korea.
  • Woom Seo D; Veterinary Medical Center and College of Veterinary Medicine, Chungbuk National University, Cheongju, Chungbuk, Republic of Korea.
  • Yon JM; Veterinary Medical Center and College of Veterinary Medicine, Chungbuk National University, Cheongju, Chungbuk, Republic of Korea.
  • Choi EK; Veterinary Medical Center and College of Veterinary Medicine, Chungbuk National University, Cheongju, Chungbuk, Republic of Korea.
  • Kim YB; Veterinary Medical Center and College of Veterinary Medicine, Chungbuk National University, Cheongju, Chungbuk, Republic of Korea.
J Biomed Res ; 31(2): 122-129, 2017 Jan 19.
Article en En | MEDLINE | ID: mdl-28808194
Since plant oils are believed to be better than animal fats for cerebrovascular and cardiovascular diseases, the effects of various plant oils and trans-fat on blood lipid profiles and ischemic stroke were investigated. Sprague-Dawley rats were fed a diet containing the oils or trans-fat, and then body weights, blood lipids, and effects on brain infarction and physical dysfunction induced by middle cerebral artery occlusion (MCAO) were analyzed. All the oils and trans-fat, except perilla oil, significantly increased body fats and body weight gain. Sesame oil and trans-fat specifically increased blood cholesterols and triglycerides, respectively, while perilla oil decreased both cholesterols and triglycerides. Perilla oil not only attenuated cerebral infarction, but also restored locomotor activity and rota-rod performances of MCAO rats. It is suggested that perilla oil among oils and fats could be the first choice to reduce the risk of metabolic syndrome and ischemic stroke.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: J Biomed Res Año: 2017 Tipo del documento: Article Pais de publicación: China
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: J Biomed Res Año: 2017 Tipo del documento: Article Pais de publicación: China