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Ichthyosis Uteri Associated with Endometrial Adenocarcinoma: A Case Report.
Bhardwaj, Nishu; Diwaker, Preeti; Gogoi, Priyanka; Wadhwa, Neelam; Mishra, Kiran.
Afiliación
  • Bhardwaj N; Junior Resident, Department of Pathology, University College of Medical Sciences and Guru Teg Bahadur Hospital, Delhi, India.
  • Diwaker P; Assistant Professor, Department of Pathology, University College of Medical Sciences and Guru Teg Bahadur Hospital, Delhi, India.
  • Gogoi P; Associate Professor, Department of Pathology, University College of Medical Sciences and Guru Teg Bahadur Hospital, Delhi, India.
  • Wadhwa N; Professor, Department of Pathology, University College of Medical Sciences and Guru Teg Bahadur Hospital, Delhi, India.
  • Mishra K; Ex-Director Professor, Department of Pathology, University College of Medical Sciences and Guru Teg Bahadur Hospital, Delhi, India.
J Clin Diagn Res ; 11(6): ED24-ED25, 2017 Jun.
Article en En | MEDLINE | ID: mdl-28764184
The replacement of the entire or extensive parts of endometrial lining by stratified squamous epithelium is a rare entity known as ichthyosis uteri. It is considered to be a benign condition but may be associated with dysplastic changes and primary squamous cell carcinoma of the endometrium. Its association with endometrial adenocarcinoma is very rare. The aetiology of this condition is not clearly understood till date. We report a case of ichthyosis uteri associated with endometrial adenocarcinoma in a 70-year-old female who presented with complaint of per-vaginal bleeding for six months and underwent hysterectomy after being diagnosed with endometrial carcinoma. Microscopic examination of sections revealed endometrioid adenocarcinoma International Federation of Gynaecology and Obstetrics (FIGO) Grade 3 along with extensive replacement of the endometrial lining by stratified squamous epithelium, consistent with ichthyosis uteri. Although ichthyosis uteri is considered benign and its malignant potential is yet to be established, its association with endometrial malignancies, both squamous and adenocarcinoma, necessitates extensive sampling of the uterus if any focus of squamous metaplasia is identified in a hysterectomy specimen, to rule out a co-existing carcinoma.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Prognostic_studies / Risk_factors_studies Idioma: En Revista: J Clin Diagn Res Año: 2017 Tipo del documento: Article País de afiliación: India Pais de publicación: India
Texto completo
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Imprimir
XML
PubMed Links
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Prognostic_studies / Risk_factors_studies Idioma: En Revista: J Clin Diagn Res Año: 2017 Tipo del documento: Article País de afiliación: India Pais de publicación: India