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Design, synthesis and biological evaluation of 4-anilinoquinoline derivatives as novel potent tubulin depolymerization agents.
Zhou, Yuanyuan; Yan, Wei; Cao, Dong; Shao, Mingfeng; Li, Dan; Wang, Fang; Yang, Zhuang; Chen, Yong; He, Linhong; Wang, Taijin; Shen, Mingsheng; Chen, Lijuan.
Afiliación
  • Zhou Y; State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University and Collaborative Innovation Center, Chengdu, 610041, China.
  • Yan W; State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University and Collaborative Innovation Center, Chengdu, 610041, China.
  • Cao D; Chengdu Institute of Chinese Herbal Medicine, Chengdu, 610043, China.
  • Shao M; State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University and Collaborative Innovation Center, Chengdu, 610041, China.
  • Li D; State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University and Collaborative Innovation Center, Chengdu, 610041, China.
  • Wang F; State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University and Collaborative Innovation Center, Chengdu, 610041, China.
  • Yang Z; State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University and Collaborative Innovation Center, Chengdu, 610041, China.
  • Chen Y; State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University and Collaborative Innovation Center, Chengdu, 610041, China.
  • He L; State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University and Collaborative Innovation Center, Chengdu, 610041, China.
  • Wang T; State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University and Collaborative Innovation Center, Chengdu, 610041, China.
  • Shen M; State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University and Collaborative Innovation Center, Chengdu, 610041, China.
  • Chen L; State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University and Collaborative Innovation Center, Chengdu, 610041, China; School of Chemical Engineering, Sichuan University, Chengdu, China. Electronic address: chenlijuan125@163.com.
Eur J Med Chem ; 138: 1114-1125, 2017 Sep 29.
Article en En | MEDLINE | ID: mdl-28763646
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Quinolinas / Tubulina (Proteína) / Diseño de Fármacos / Compuestos de Anilina / Antineoplásicos Límite: Animals / Humans Idioma: En Revista: Eur J Med Chem Año: 2017 Tipo del documento: Article País de afiliación: China Pais de publicación: Francia
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Quinolinas / Tubulina (Proteína) / Diseño de Fármacos / Compuestos de Anilina / Antineoplásicos Límite: Animals / Humans Idioma: En Revista: Eur J Med Chem Año: 2017 Tipo del documento: Article País de afiliación: China Pais de publicación: Francia