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The role of microRNAs in different types of thyroid carcinoma: a comprehensive analysis to find new miRNA supplementary therapies.
Pishkari, S; Paryan, M; Hashemi, M; Baldini, E; Mohammadi-Yeganeh, S.
Afiliación
  • Pishkari S; Department of Medicine, Tehran Medical Sciences Branch, Islamic Azad University, Tehran, Iran.
  • Paryan M; Department of Research and Development, Production and Research Complex, Pasteur Institute of Iran, Tehran, Iran.
  • Hashemi M; Department of Medicine, Tehran Medical Sciences Branch, Islamic Azad University, Tehran, Iran.
  • Baldini E; Department of Surgical Sciences, University of Rome, Rome, Italy. baldinienke@virgilio.it.
  • Mohammadi-Yeganeh S; Cellular and Molecular Biology Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran. s.mohammadiyeganeh@sbmu.ac.ir.
J Endocrinol Invest ; 41(3): 269-283, 2018 Mar.
Article en En | MEDLINE | ID: mdl-28762013
The most common endocrine malignancy is thyroid cancer, and researchers have made a great deal of progress in deciphering its molecular mechanisms in the recent years. Many of molecular changes observed in thyroid cancer can be used as biomarkers for diagnosis, prognosis, and therapeutic targets for treatment. MicroRNAs (miRNAs) are important parts in biological and metabolic pathways such as regulation of developmental stages, signal transduction, cell maintenance, and differentiation. Therefore, their dysregulation can expose individuals to malignancies. It has been proved that miRNA expression is dysregulated in different types of tumors, like thyroid cancers, and can be the cause of tumor initiation and progression. In this paper, we have reviewed the available data on miRNA dysregulation in different thyroid tumors including papillary, follicular, anaplastic, and medullary thyroid carcinomas aiming to introduce the last updates in miRNAs-thyroid cancer relation.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias de la Tiroides / MicroARNs Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: J Endocrinol Invest Año: 2018 Tipo del documento: Article País de afiliación: Irán Pais de publicación: Italia
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias de la Tiroides / MicroARNs Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: J Endocrinol Invest Año: 2018 Tipo del documento: Article País de afiliación: Irán Pais de publicación: Italia