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A marine sponge alkaloid derivative 4-chloro fascaplysin inhibits tumor growth and VEGF mediated angiogenesis by disrupting PI3K/Akt/mTOR signaling cascade.
Sharma, Sonia; Guru, Santosh Kumar; Manda, Sudhakar; Kumar, Ashok; Mintoo, Mubashir J; Prasad, Venna Deva; Sharma, Parduman R; Mondhe, Dilip M; Bharate, Sandip B; Bhushan, Shashi.
Afiliación
  • Sharma S; Academy of Scientific and Innovative Research (AcSIR), Anusandhan Bhawan, 2 Rafi Marg, New Delhi, India; Cancer Pharmacology Division, Indian Institute of Integrative Medicine, CSIR, Jammu 180001, India.
  • Guru SK; Cancer Pharmacology Division, Indian Institute of Integrative Medicine, CSIR, Jammu 180001, India; Department of Molecular Cell and Cancer Biology, University of Massachusetts Medical School, MA, 01605, USA.
  • Manda S; Academy of Scientific and Innovative Research (AcSIR), Anusandhan Bhawan, 2 Rafi Marg, New Delhi, India; Medicinal Chemistry Division, CSIR-Indian Institute of Integrative Medicine, Canal Road, Jammu 180001, India.
  • Kumar A; Academy of Scientific and Innovative Research (AcSIR), Anusandhan Bhawan, 2 Rafi Marg, New Delhi, India; Cancer Pharmacology Division, Indian Institute of Integrative Medicine, CSIR, Jammu 180001, India.
  • Mintoo MJ; Academy of Scientific and Innovative Research (AcSIR), Anusandhan Bhawan, 2 Rafi Marg, New Delhi, India; Cancer Pharmacology Division, Indian Institute of Integrative Medicine, CSIR, Jammu 180001, India.
  • Prasad VD; Cancer Pharmacology Division, Indian Institute of Integrative Medicine, CSIR, Jammu 180001, India.
  • Sharma PR; Cancer Pharmacology Division, Indian Institute of Integrative Medicine, CSIR, Jammu 180001, India.
  • Mondhe DM; Academy of Scientific and Innovative Research (AcSIR), Anusandhan Bhawan, 2 Rafi Marg, New Delhi, India; Cancer Pharmacology Division, Indian Institute of Integrative Medicine, CSIR, Jammu 180001, India.
  • Bharate SB; Academy of Scientific and Innovative Research (AcSIR), Anusandhan Bhawan, 2 Rafi Marg, New Delhi, India; Medicinal Chemistry Division, CSIR-Indian Institute of Integrative Medicine, Canal Road, Jammu 180001, India.
  • Bhushan S; Academy of Scientific and Innovative Research (AcSIR), Anusandhan Bhawan, 2 Rafi Marg, New Delhi, India; Cancer Pharmacology Division, Indian Institute of Integrative Medicine, CSIR, Jammu 180001, India; Department of Phytopharmaceutical & RSD, Indian Pharmacopoeia Commission (IPC), MH&FW, G
Chem Biol Interact ; 275: 47-60, 2017 Sep 25.
Article en En | MEDLINE | ID: mdl-28756150
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Poríferos / Transducción de Señal / Neovascularización Fisiológica / Factor A de Crecimiento Endotelial Vascular / Indoles Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: Chem Biol Interact Año: 2017 Tipo del documento: Article País de afiliación: India Pais de publicación: Irlanda
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Poríferos / Transducción de Señal / Neovascularización Fisiológica / Factor A de Crecimiento Endotelial Vascular / Indoles Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: Chem Biol Interact Año: 2017 Tipo del documento: Article País de afiliación: India Pais de publicación: Irlanda