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Pharmaceuticals released from senior residences: occurrence and risk evaluation.
Lacorte, Silvia; Luis, Silvia; Gómez-Canela, Cristian; Sala-Comorera, Teresa; Courtier, Audrey; Roig, Benoit; Oliveira-Brett, Ana Maria; Joannis-Cassan, Claire; Aragonés, Juan Ignacio; Poggio, Lucia; Noguer, Thierry; Lima, Luisa; Barata, Carlos; Calas-Blanchard, Carole.
Afiliación
  • Lacorte S; Department of Environmental Chemistry, IDAEA-CSIC, Jordi Girona 18-26, 08034, Barcelona, Catalonia, Spain. slbqam@cid.csic.es.
  • Luis S; Centro de Investigação e Intervenção Social (CIS-IUL), Instituto Universitário de Lisboa (ISCTE-IUL), Lisbon, Portugal.
  • Gómez-Canela C; Department of Environmental Chemistry, IDAEA-CSIC, Jordi Girona 18-26, 08034, Barcelona, Catalonia, Spain.
  • Sala-Comorera T; Department of Environmental Chemistry, IDAEA-CSIC, Jordi Girona 18-26, 08034, Barcelona, Catalonia, Spain.
  • Courtier A; EA7352 CHROME, Université de Nimes, Rue du Dr Georges Salan, 30021, Nimes, France.
  • Roig B; EA7352 CHROME, Université de Nimes, Rue du Dr Georges Salan, 30021, Nimes, France.
  • Oliveira-Brett AM; Department of Chemistry, University of Coimbra, 3004-535, Coimbra, Portugal.
  • Joannis-Cassan C; INPT; CNRS; LGC (Laboratoire de Génie Chimique), Université de Toulouse, 4, Allée Emile Monso, 31030, Toulouse, France.
  • Aragonés JI; Facultad de Psicología, Universidad Complutense de Madrid, Madrid, Spain.
  • Poggio L; Facultad de Psicología, Universidad Complutense de Madrid, Madrid, Spain.
  • Noguer T; Laboratoire Biocapteurs, Analyses, Environnement, BAE-LBBM USR 3579, Université de Perpignan Via Domitia, 52 Av Paul Alduy, 66860, Perpignan cedex, France.
  • Lima L; Centro de Investigação e Intervenção Social (CIS-IUL), Instituto Universitário de Lisboa (ISCTE-IUL), Lisbon, Portugal.
  • Barata C; Department of Environmental Chemistry, IDAEA-CSIC, Jordi Girona 18-26, 08034, Barcelona, Catalonia, Spain.
  • Calas-Blanchard C; Laboratoire Biocapteurs, Analyses, Environnement, BAE-LBBM USR 3579, Université de Perpignan Via Domitia, 52 Av Paul Alduy, 66860, Perpignan cedex, France.
Environ Sci Pollut Res Int ; 25(7): 6095-6106, 2018 Mar.
Article en En | MEDLINE | ID: mdl-28748440
One of the main pursuits, yet most difficult, in monitoring studies is to identify the sources of environmental pollution. In this study, we have identified health-care facilities from south European countries as an important source of pharmaceuticals in the environment. We have estimated that compounds consumed in by the elderly and released from effluents of senior residences can reach river waters at a concentration higher than 0.01 µg/L, which is the European Medicines Agency (EMA) threshold for risk evaluation of pharmaceuticals in surface waters. This study has been based on five health institutions in Portugal, Spain, and France, with 52 to 130 beds. We have compiled the pharmaceuticals dispensed on a daily base and calculated the consumption rates. From 54.9 to 1801 g of pharmaceuticals are consumed daily, with laxatives, analgesics, antiepileptics, antibiotics, and antidiabetic agents being the main drug families administered. According to excretion rates, dilution in the sewerage system, and elimination in wastewater treatment plants, macrogol, metformin, paracetamol, acetylcysteine, amoxicillin, and gabapentin, among others, are expected to reach river waters. Finally, we discuss the risk management actions related to the discharge of pharmaceuticals from senior residences to surface waters.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Contaminantes Químicos del Agua / Preparaciones Farmacéuticas / Monitoreo del Ambiente / Viviendas para Ancianos / Aguas Residuales / Hogares para Ancianos Tipo de estudio: Etiology_studies / Prognostic_studies / Risk_factors_studies Límite: Aged / Humans País/Región como asunto: Europa Idioma: En Revista: Environ Sci Pollut Res Int Asunto de la revista: SAUDE AMBIENTAL / TOXICOLOGIA Año: 2018 Tipo del documento: Article País de afiliación: España Pais de publicación: Alemania
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Contaminantes Químicos del Agua / Preparaciones Farmacéuticas / Monitoreo del Ambiente / Viviendas para Ancianos / Aguas Residuales / Hogares para Ancianos Tipo de estudio: Etiology_studies / Prognostic_studies / Risk_factors_studies Límite: Aged / Humans País/Región como asunto: Europa Idioma: En Revista: Environ Sci Pollut Res Int Asunto de la revista: SAUDE AMBIENTAL / TOXICOLOGIA Año: 2018 Tipo del documento: Article País de afiliación: España Pais de publicación: Alemania