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Large Cell Transformation of Oral Mycosis Fungoides.
Sultan, Ahmed S; Mostoufi, Behzad; Papadimitriou, John C; Koka, Rima; Basile, John; Younis, Rania H.
Afiliación
  • Sultan AS; Department of Oncology and Diagnostic Sciences, School of Dentistry, University of Maryland, Baltimore, MD, 21201, USA. asultan@umaryland.edu.
  • Mostoufi B; Department of Oral and Maxillofacial Surgery, School of Dentistry, University of Maryland, Baltimore, MD, 21201, USA.
  • Papadimitriou JC; Department of Pathology, University of Maryland School of Medicine, Baltimore, MD, 21201, USA.
  • Koka R; Department of Pathology, University of Maryland School of Medicine, Baltimore, MD, 21201, USA.
  • Basile J; Department of Oncology and Diagnostic Sciences, School of Dentistry, University of Maryland, Baltimore, MD, 21201, USA.
  • Younis RH; University of Maryland Greenebaum Cancer Center, Baltimore, MD, 21201, USA.
Head Neck Pathol ; 12(2): 247-251, 2018 Jun.
Article en En | MEDLINE | ID: mdl-28741231
Mycosis fungoides (MF) accounts for approximately 50% of all primary cutaneous lymphomas. MF occurrence in the oral cavity is extremely rare with approximately 45 cases reported to date. We present a case of a 68 year-old man with a raised nodular lesion of the ventral tongue with clinical impression of irritational fibroma. Histopathologic and immunohistochemical (IHC) examination revealed a phenotype consistent with MF with large cell transformation in the context of Sezary syndrome. The histological diagnosis of oral MF requires a high index of suspicion and IHC panel to rule out large cell transformation. To our knowledge, only four cases of large cell transformation of oral MF have been reported in the English literature. The clinical and histopathologic features of a rare case of intra-oral MF with large cell transformation are exemplified in this article.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias Cutáneas / Neoplasias de la Boca / Transformación Celular Neoplásica / Micosis Fungoide / Síndrome de Sézary Límite: Aged / Humans / Male Idioma: En Revista: Head Neck Pathol Asunto de la revista: NEOPLASIAS / PATOLOGIA Año: 2018 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias Cutáneas / Neoplasias de la Boca / Transformación Celular Neoplásica / Micosis Fungoide / Síndrome de Sézary Límite: Aged / Humans / Male Idioma: En Revista: Head Neck Pathol Asunto de la revista: NEOPLASIAS / PATOLOGIA Año: 2018 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos