Role of Mesenchymal Stem Cells in Cancer Development and Their Use in Cancer Therapy.

Serakinci, Nedime; Tulay, Pinar; Kalkan, Rasime

Serakinci, Nedime; Tulay, Pinar; Kalkan, Rasime.

Afiliación

Serakinci N; Faculty of Medicine, Department of Medical Genetics, Near East University, Nicosia, Cyprus. nedimeserakinci@gmail.com.
Tulay P; Faculty of Arts and Sciences, Department of Molecular Biology and Genetics, Near East University, Nicosia, Cyprus. nedimeserakinci@gmail.com.
Kalkan R; Faculty of Medicine, Department of Medical Genetics, Near East University, Nicosia, Cyprus.

Adv Exp Med Biol ; 1083: 45-62, 2018.

Article en En | MEDLINE | ID: mdl-28730382

RESUMEN

Stem cells have the ability to perpetuate themselves through self-renewal and generate mature cells of a particular tissue through differentiation. Mesenchymal stem cells (MSCs) play an important role in tissue homeostasis - supporting tissue regeneration. MSCs are rare pluripotent cells supporting hematopoietic and mesenchymal cell lineages. MSCs have a great therapeutic potential in cancer therapy, as well as stem cell exosome and/or microvesicle-mediated tissue regeneration. In this review, the use of hMSCs in stem cell-mediated cancer therapy is discussed.

Asunto(s)

Trasplante de Células Madre Mesenquimatosas; Células Madre Mesenquimatosas/citología; Neoplasias/terapia; Diferenciación Celular; Humanos

Palabras clave

Cancer development; Cancer therapy; Mesenchymal stem cells; Stem cell-mediated cancer therapy

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Trasplante de Células Madre Mesenquimatosas / Células Madre Mesenquimatosas / Neoplasias Límite: Humans Idioma: En Revista: Adv Exp Med Biol Año: 2018 Tipo del documento: Article País de afiliación: Chipre Pais de publicación: Estados Unidos

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