[Scaffold-based Bone Tissue Engineering]. / Gerüstträgerbasiertes Knochen-Tissue-Engineering.
Orthopade
; 46(8): 701-710, 2017 Aug.
Article
en De
| MEDLINE
| ID: mdl-28725934
Tissue engineering provides the possibility of regenerating damaged or lost osseous structures without the need for permanent implants. Within this context, biodegradable and bioresorbable scaffolds can provide structural and biomechanical stability until the body's own tissue can take over their function. Additive biomanufacturing makes it possible to design the scaffold's architectural characteristics to specifically guide tissue formation and regeneration. Its nano-, micro-, and macro-architectural properties can be tailored to ensure vascularization, oxygenation, nutrient supply, waste exchange, and eventually ossification not only in its periphery but also in its center, which is not in direct contact with osteogenic elements of the surrounding healthy tissue. In this article we provide an overview about our conceptual design and process of the clinical translation of scaffold-based bone tissue engineering applications.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Huesos
/
Ingeniería de Tejidos
/
Andamios del Tejido
Tipo de estudio:
Prognostic_studies
Límite:
Humans
Idioma:
De
Revista:
Orthopade
Año:
2017
Tipo del documento:
Article
Pais de publicación:
Alemania