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Application of Carbon Nanotubes in Chiral and Achiral Separations of Pharmaceuticals, Biologics and Chemicals.
Hemasa, Ayman L; Naumovski, Nenad; Maher, William A; Ghanem, Ashraf.
Afiliación
  • Hemasa AL; Chirality Program, Biomedical Science, University of Canberra, Bruce, Australian Capital Territory (ACT) 2617, Australia. Ayman.Hemasa@canberra.edu.au.
  • Naumovski N; Collaborative Research in Bioactives and Biomarkers Group (CRIBB), University of Canberra, Bruce, Australian Capital Territory (ACT) 2617, Australia. Nenad.Naumovski@canberra.edu.au.
  • Maher WA; Ecochemistry Laboratory, Institute for Applied Ecology, University of Canberra, Bruce, Australian Capital Territory (ACT) 2617, Australia. Bill.Maher@canberra.edu.au.
  • Ghanem A; Chirality Program, Biomedical Science, University of Canberra, Bruce, Australian Capital Territory (ACT) 2617, Australia. ashraf.ghanem@canberra.edu.au.
Nanomaterials (Basel) ; 7(7)2017 Jul 18.
Article en En | MEDLINE | ID: mdl-28718832
Carbon nanotubes (CNTs) possess unique mechanical, physical, electrical and absorbability properties coupled with their nanometer dimensional scale that renders them extremely valuable for applications in many fields including nanotechnology and chromatographic separation. The aim of this review is to provide an updated overview about the applications of CNTs in chiral and achiral separations of pharmaceuticals, biologics and chemicals. Chiral single-walled carbon nanotubes (SWCNTs) and multi-walled carbon nanotubes (MWCNTs) have been directly applied for the enantioseparation of pharmaceuticals and biologicals by using them as stationary or pseudostationary phases in chromatographic separation techniques such as high-performance liquid chromatography (HPLC), capillary electrophoresis (CE) and gas chromatography (GC). Achiral MWCNTs have been used for achiral separations as efficient sorbent objects in solid-phase extraction techniques of biochemicals and drugs. Achiral SWCNTs have been applied in achiral separation of biological samples. Achiral SWCNTs and MWCNTs have been also successfully used to separate achiral mixtures of pharmaceuticals and chemicals. Collectively, functionalized CNTs have been indirectly applied in separation science by enhancing the enantioseparation of different chiral selectors whereas non-functionalized CNTs have shown efficient capabilities for chiral separations by using techniques such as encapsulation or immobilization in polymer monolithic columns.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Nanomaterials (Basel) Año: 2017 Tipo del documento: Article País de afiliación: Australia Pais de publicación: Suiza
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Nanomaterials (Basel) Año: 2017 Tipo del documento: Article País de afiliación: Australia Pais de publicación: Suiza