Mathematical Simulation of Transport Kinetics of Tumor-Imaging Radiopharmaceutical <sup>99m</sup>Tc-MIBI.

Shevtsova, O N; Shevtsova, V K

Mathematical Simulation of Transport Kinetics of Tumor-Imaging Radiopharmaceutical ^99mTc-MIBI.

Shevtsova, O N; Shevtsova, V K.

Afiliación

Shevtsova ON; Institute for Safety Problems of NPP, The National Academy of Sciences of Ukraine, Lisogirskaya Str. 12, Kyiv, Ukraine.
Shevtsova VK; National Medical University of O.O. Bogomolets, Pr. Peremogi 34, Kyiv, Ukraine.

Comput Math Methods Med ; 2017: 2414878, 2017.

Article en En | MEDLINE | ID: mdl-28702073

RESUMEN

The proposed model describes in a quality way the process of tumor-imaging radiopharmaceutical 99mTc-MIBI distribution with taking into account radiopharmaceutical accumulation, elimination, and radioactive decay. The dependencies of concentration versus the time are analyzed. The model can be easily tested by the concentration data of the radioactive pharmaceuticals in the blood measured at early time point and late time point of the scanning, and the obtained data can be used for determination of the washout rate coefficient which is one of the existing oncology diagnostics methods.

Asunto(s)

Simulación por Computador; Modelos Teóricos; Tecnecio Tc 99m Sestamibi/metabolismo; Humanos; Cinética; Cintigrafía; Radiofármacos/metabolismo

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Simulación por Computador / Tecnecio Tc 99m Sestamibi / Modelos Teóricos Límite: Humans Idioma: En Revista: Comput Math Methods Med Asunto de la revista: INFORMATICA MEDICA Año: 2017 Tipo del documento: Article País de afiliación: Ucrania Pais de publicación: Estados Unidos

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