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Discovery of novel naphthoquinone derivatives as inhibitors of the tumor cell specific M2 isoform of pyruvate kinase.
Ning, Xianling; Qi, Hailong; Li, Ridong; Li, Yunqiao; Jin, Yan; McNutt, Michael A; Liu, Junyi; Yin, Yuxin.
Afiliación
  • Ning X; Institute of Systems Biomedicine, School of Basic Medical Sciences, Peking University Health Science Center, Beijing, China; Department of Pharmacology, School of Basic Medical Sciences, Peking University Health Science Center, Beijing, China.
  • Qi H; Institute of Systems Biomedicine, School of Basic Medical Sciences, Peking University Health Science Center, Beijing, China; Peking-Tsinghua Center for Life Sciences, Peking University Health Science Center, Beijing, China.
  • Li R; Institute of Systems Biomedicine, School of Basic Medical Sciences, Peking University Health Science Center, Beijing, China; Department of Pharmacology, School of Basic Medical Sciences, Peking University Health Science Center, Beijing, China.
  • Li Y; Institute of Systems Biomedicine, School of Basic Medical Sciences, Peking University Health Science Center, Beijing, China; Department of Pathology, School of Basic Medical Sciences, Peking University Health Science Center, Beijing, China.
  • Jin Y; Institute of Systems Biomedicine, School of Basic Medical Sciences, Peking University Health Science Center, Beijing, China; Department of Pathology, School of Basic Medical Sciences, Peking University Health Science Center, Beijing, China.
  • McNutt MA; Institute of Systems Biomedicine, School of Basic Medical Sciences, Peking University Health Science Center, Beijing, China; Peking-Tsinghua Center for Life Sciences, Peking University Health Science Center, Beijing, China; Department of Pathology, School of Basic Medical Sciences, Peking University
  • Liu J; State Key Laboratory of Natural and Biomimetic Drugs, Department of Chemical Biology, School of Pharmaceutical Sciences, Peking University Health Science Center, Beijing, China.
  • Yin Y; Institute of Systems Biomedicine, School of Basic Medical Sciences, Peking University Health Science Center, Beijing, China; Peking-Tsinghua Center for Life Sciences, Peking University Health Science Center, Beijing, China; Department of Pathology, School of Basic Medical Sciences, Peking University
Eur J Med Chem ; 138: 343-352, 2017 Sep 29.
Article en En | MEDLINE | ID: mdl-28688274
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Piruvato Quinasa / Naftoquinonas / Inhibidores de Proteínas Quinasas / Descubrimiento de Drogas Límite: Humans Idioma: En Revista: Eur J Med Chem Año: 2017 Tipo del documento: Article País de afiliación: China Pais de publicación: Francia
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Piruvato Quinasa / Naftoquinonas / Inhibidores de Proteínas Quinasas / Descubrimiento de Drogas Límite: Humans Idioma: En Revista: Eur J Med Chem Año: 2017 Tipo del documento: Article País de afiliación: China Pais de publicación: Francia