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Inhibition of the B7-H3 immune checkpoint limits tumor growth by enhancing cytotoxic lymphocyte function.
Lee, Young-Hee; Martin-Orozco, Natalia; Zheng, Peilin; Li, Jing; Zhang, Peng; Tan, Haidong; Park, Hyun Jung; Jeong, Mira; Chang, Seon Hee; Kim, Byung-Seok; Xiong, Wei; Zang, Wenjuan; Guo, Li; Liu, Yang; Dong, Zhong-Jun; Overwijk, Willem W; Hwu, Patrick; Yi, Qing; Kwak, Larry; Yang, Zhiying; Mak, Tak W; Li, Wei; Radvanyi, Laszlo G; Ni, Ling; Liu, Dongfang; Dong, Chen.
Afiliación
  • Lee YH; Department of Immunology.
  • Martin-Orozco N; Department of Immunology.
  • Zheng P; EMD Serono Research and Development Institute, Inc. 45A Middlesex Turnpike, Billerica, MA 01821, USA.
  • Li J; Center for Inflammation and Epigenetics, Houston Methodist Research Institute, 6670 Bertner Ave, Houston, TX 77030, USA.
  • Zhang P; Department of Microbiology and Immunology, Weill Cornell Medical College, Cornell University, New York, NY 10065, USA.
  • Tan H; The Second Xiangya Hospital, Central South University, Key Laboratory of Diabetes Immunology, Ministry of Education, National Clinical Research Center for Metabolic Diseases, 139 Renmin Road, Changsha, Hunan 410011, China.
  • Park HJ; Institute for Immunology and School of Medicine, Tsinghua University, Beijing, 100084, China.
  • Jeong M; Center for Cancer and Immunology Research, Children's National Health System, Washington DC, 20010 USA.
  • Chang SH; Department of Hepatobiliary Surgery, China-Japan Friendship Hospital, Beijing, 100029, China.
  • Kim BS; Department of Molecular and Cellular Biology.
  • Xiong W; Department of Pathology and Immunology, Baylor College of Medicine, Houston, TX 77030, USA.
  • Zang W; Department of Immunology.
  • Guo L; Department of Immunology.
  • Liu Y; Department of Microbiology and Immunology, Weill Cornell Medical College, Cornell University, New York, NY 10065, USA.
  • Dong ZJ; The Second Xiangya Hospital, Central South University, Key Laboratory of Diabetes Immunology, Ministry of Education, National Clinical Research Center for Metabolic Diseases, 139 Renmin Road, Changsha, Hunan 410011, China.
  • Overwijk WW; Institute for Immunology and School of Medicine, Tsinghua University, Beijing, 100084, China.
  • Hwu P; X-KANG United Biopharmaceutical Science &Technology Co. Ltd., Suzhou, Jiangsu 215000, China.
  • Yi Q; Center for Cancer and Immunology Research, Children's National Health System, Washington DC, 20010 USA.
  • Kwak L; Institute for Immunology and School of Medicine, Tsinghua University, Beijing, 100084, China.
  • Yang Z; Department of Melanoma.
  • Mak TW; Department of Melanoma.
  • Li W; Departments of Lymphoma and Myeloma, U.T. MD Anderson Cancer Center, 7455 Fannin St., Houston, TX 77054, USA.
  • Radvanyi LG; Department of Cancer Biology Betsy B. DeWindt Endowed Chair for Cancer Research, Lerner Research Institute, Cleveland Clinic, 9500 Euclid Avenue, Cleveland, OH 44195, USA.
  • Ni L; Departments of Lymphoma and Myeloma, U.T. MD Anderson Cancer Center, 7455 Fannin St., Houston, TX 77054, USA.
  • Liu D; City of Hope National Medical Center, 1500 East Duarte Road, Duarte, CA, 91010, USA.
  • Dong C; Department of Hepatobiliary Surgery, China-Japan Friendship Hospital, Beijing, 100029, China.
Cell Res ; 27(8): 1034-1045, 2017 Aug.
Article en En | MEDLINE | ID: mdl-28685773
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Células Asesinas Naturales / Linfocitos T CD8-positivos / Antígenos B7 / Inmunidad Celular / Proteínas de Neoplasias / Neoplasias Límite: Animals / Female / Humans / Male Idioma: En Revista: Cell Res Año: 2017 Tipo del documento: Article Pais de publicación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Células Asesinas Naturales / Linfocitos T CD8-positivos / Antígenos B7 / Inmunidad Celular / Proteínas de Neoplasias / Neoplasias Límite: Animals / Female / Humans / Male Idioma: En Revista: Cell Res Año: 2017 Tipo del documento: Article Pais de publicación: Reino Unido