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Correlation of serum anti-Mullerian hormone to follicular follicle stimulating hormone and implantation potential of the ensuing embryos.
Lee, Maw-Sheng; Tzeng, Shu-Ling; Yang, Shun-Fa; Lin, Yi-Ping; Cheng, En-Hui; Huang, Chun-Chia; Yang, Yu-Shih; Lee, Tsung-Hsien.
Afiliación
  • Lee MS; Institute of Medicine, School of Medicine, Chung Shan Medical University, 402 Taichung, Taiwan; Department of Obstetrics and Gynecology, School of Medicine, Chung Shan Medical University, 402 Taichung, Taiwan; Division of Infertility Clinic, Lee Women's Hospital, 406 Taichung, Taiwan.
  • Tzeng SL; Institute of Medicine, School of Medicine, Chung Shan Medical University, 402 Taichung, Taiwan.
  • Yang SF; Institute of Medicine, School of Medicine, Chung Shan Medical University, 402 Taichung, Taiwan.
  • Lin YP; Division of Infertility Clinic, Lee Women's Hospital, 406 Taichung, Taiwan.
  • Cheng EH; Division of Infertility Clinic, Lee Women's Hospital, 406 Taichung, Taiwan.
  • Huang CC; Division of Infertility Clinic, Lee Women's Hospital, 406 Taichung, Taiwan.
  • Yang YS; Department of Obstetrics and Gynecology, National Taiwan University, National Taiwan University Hospital, 100 Taipei, Taiwan.
  • Lee TH; Institute of Medicine, School of Medicine, Chung Shan Medical University, 402 Taichung, Taiwan; Department of Obstetrics and Gynecology, School of Medicine, Chung Shan Medical University, 402 Taichung, Taiwan; Division of Infertility Clinic, Lee Women's Hospital, 406 Taichung, Taiwan; Department of
Clin Chim Acta ; 471: 327-333, 2017 Aug.
Article en En | MEDLINE | ID: mdl-28684220
Serum anti-Mullerian hormone (AMH) is a predictor of the pregnancy outcome in assisted reproductive technology (ART) cycles, particularly for older women. This study attempts to elucidate the effect of serum AMH on follicular hormone profiles and implantation outcome of the ensuing embryos in ART cycles. A total of 412 patients undergoing ART cycles at a private infertility center were included and 780 follicular fluid samples were collected. Levels of follicular hormones, including FSH, LH, inhibin B, AMH, estradiol, progesterone, and androstenedione were measured. The implantation outcome of the ensuing embryos was traced as a main outcome measure. We demonstrated that the follicular levels of estradiol, progesterone, and androstenedione were considerably similar, but the overall implantation rates increased as the serum AMH increased. Logistic regression analysis revealed that the best predictor for embryo implantation was follicular FSH (>9.64mIU/mL, odds ratio [OR] 0.9). Furthermore, serum AMH (Spearman's rho=-0.352) and female age (rho=0.369) are correlated with follicular FSH levels in those follicles. In conclusion, the serum AMH might affect follicular hormone profiles by interaction with gonadotrophin rather than with steroidogenesis. The follicular FSH levels are correlated with the implantation potential of the ensuing embryos.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Implantación del Embrión / Hormona Antimülleriana / Hormona Folículo Estimulante Tipo de estudio: Prognostic_studies Límite: Adult / Female / Humans / Pregnancy Idioma: En Revista: Clin Chim Acta Año: 2017 Tipo del documento: Article País de afiliación: Taiwán Pais de publicación: Países Bajos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Implantación del Embrión / Hormona Antimülleriana / Hormona Folículo Estimulante Tipo de estudio: Prognostic_studies Límite: Adult / Female / Humans / Pregnancy Idioma: En Revista: Clin Chim Acta Año: 2017 Tipo del documento: Article País de afiliación: Taiwán Pais de publicación: Países Bajos