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Non-invasive ventilation improves hemorheology status in hypoxemic patients with acute myocardial infarction after PCI.
Wang, Xi-Fu; Ye, Ming; Yan, Dong; Zhang, Hui-Min; Jia, Ping; Ren, Xue-Jun; Zeng, Yu-Jie.
Afiliación
  • Wang XF; Department of Emergency and Critical Care Center, Beijing Anzhen Hospital, Capital Medical University, Beijing, China.
  • Ye M; Department of Emergency and Critical Care Center, Beijing Anzhen Hospital, Capital Medical University, Beijing, China.
  • Yan D; Department of Cardiology, Peking University Shougang Hospital, Beijing, China.
  • Zhang HM; Department of Emergency and Critical Care Center, Beijing Anzhen Hospital, Capital Medical University, Beijing, China.
  • Jia P; Department of Emergency and Critical Care Center, Beijing Anzhen Hospital, Capital Medical University, Beijing, China.
  • Ren XJ; Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University, Beijing, China.
  • Zeng YJ; Department of Emergency and Critical Care Center, Beijing Anzhen Hospital, Capital Medical University, Beijing, China.
J Geriatr Cardiol ; 14(4): 274-279, 2017 Apr.
Article en En | MEDLINE | ID: mdl-28663766
BACKGROUND: Hypoxemia sometimes occurs in the emergency room in the patients with acute myocardial infarction (AMI) after percutaneous coronary intervention (PCI), even in those with administration of conventional high-flow oxygen inhalation. The objective of the present study was to evaluate the effectiveness of non-invasive ventilation (NIV) in improving blood oxygen content and hemorheology in patients with AMI and hypoxemia. METHODS: This prospective study enrolled 50 consecutive eligible patients with AMI (aged 72.3 ± 9.5 years), who had undergone PCI and been administered high-flow oxygen but still had hypoxemia. Blood was taken before NIV and at 0.5, 1, and 2 h after NIV. Blood gases, hemorheological variables including erythrocyte deformability, erythrocyte aggregation, erythrocyte osmotic fragility, membrane fluidity, and oxidative stress level were measured. RESULTS: Blood PaO2 increased to normal by 1 h after NIV. Assessed hemorheological variables had all improved and plasma malondialdehyde concentration decreased significantly after 2 h of NIV. CONCLUSIONS: Our data suggest that NIV can help to improve blood oxygen content, hemorheological status, and minimize plasma lipid peroxidation injury in hypoxemic patients with AMI who have undergone PCI.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Observational_studies Idioma: En Revista: J Geriatr Cardiol Año: 2017 Tipo del documento: Article País de afiliación: China Pais de publicación: China
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Observational_studies Idioma: En Revista: J Geriatr Cardiol Año: 2017 Tipo del documento: Article País de afiliación: China Pais de publicación: China