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Dental implants in patients with osteoporosis: a systematic review with meta-analysis.
de Medeiros, F C F L; Kudo, G A H; Leme, B G; Saraiva, P P; Verri, F R; Honório, H M; Pellizzer, E P; Santiago Junior, J F.
Afiliación
  • de Medeiros FCFL; Pró-Reitoria de Pesquisa e Pós-graduação (PRPPG), Universidade do Sagrado Coração, Bauru, SP, Brazil.
  • Kudo GAH; Pró-Reitoria de Pesquisa e Pós-graduação (PRPPG), Universidade do Sagrado Coração, Bauru, SP, Brazil.
  • Leme BG; Pró-Reitoria de Pesquisa e Pós-graduação (PRPPG), Universidade do Sagrado Coração, Bauru, SP, Brazil.
  • Saraiva PP; Pró-Reitoria de Pesquisa e Pós-graduação (PRPPG), Universidade do Sagrado Coração, Bauru, SP, Brazil.
  • Verri FR; Dental School of Araçatuba, UNESP - Universidade Estadual Paulista, Araçatuba, São Paulo, Brazil.
  • Honório HM; Department of Scientific Methodology and Statistics, Bauru School of Dentistry, USP - University of São Paulo, São Paulo, Brazil.
  • Pellizzer EP; Dental School of Araçatuba, UNESP - Universidade Estadual Paulista, Araçatuba, São Paulo, Brazil.
  • Santiago Junior JF; Pró-Reitoria de Pesquisa e Pós-graduação (PRPPG), Universidade do Sagrado Coração, Bauru, SP, Brazil. Electronic address: jf.santiagojunior@gmail.com.
Int J Oral Maxillofac Surg ; 47(4): 480-491, 2018 Apr.
Article en En | MEDLINE | ID: mdl-28651805
There is currently no consensus regarding the survival rate of osseointegrated implants in patients with osteoporosis. A systematic review with meta-analysis was performed to evaluate the survival rate of implants in such patients. The PubMed/MEDLINE, Web of Science, Cochrane Library, and SciELO databases were used to identify articles published up to September 2016. The systematic review was performed in accordance with PRISMA/PICO requirements and the risk of bias was assessed (Australian National Health and Medical Research Council scale). The relative risk (RR) of implant failure and mean marginal bone loss were analyzed within a 95% confidence interval (CI). Fifteen studies involving 8859 patients and 29,798 implants were included. The main outcome of the meta-analysis indicated that there was no difference in implant survival rate between patients with and without osteoporosis, either at the implant level (RR 1.39, 95% CI 0.93-2.08; P=0.11) or at the patient level (RR 0.98, 95% CI 0.50-1.89; P=0.94). However, the meta-analysis for the secondary outcome revealed a significant difference in marginal bone loss around implants between patients with and without osteoporosis (0.18mm, 95% CI 0.05-0.30, P=0.005). Data heterogeneity was low. An increase in peri-implant bone loss was observed in the osteoporosis group. Randomized and controlled clinical studies should be conducted to analyze possible biases.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Osteoporosis / Implantes Dentales / Fracaso de la Restauración Dental / Implantación Dental Endoósea Tipo de estudio: Clinical_trials / Etiology_studies / Systematic_reviews Límite: Humans Idioma: En Revista: Int J Oral Maxillofac Surg Asunto de la revista: ODONTOLOGIA Año: 2018 Tipo del documento: Article País de afiliación: Brasil Pais de publicación: Dinamarca
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Osteoporosis / Implantes Dentales / Fracaso de la Restauración Dental / Implantación Dental Endoósea Tipo de estudio: Clinical_trials / Etiology_studies / Systematic_reviews Límite: Humans Idioma: En Revista: Int J Oral Maxillofac Surg Asunto de la revista: ODONTOLOGIA Año: 2018 Tipo del documento: Article País de afiliación: Brasil Pais de publicación: Dinamarca