Bioprinted three dimensional human tissues for toxicology and disease modeling.
Drug Discov Today Technol
; 23: 37-44, 2017 Mar.
Article
en En
| MEDLINE
| ID: mdl-28647084
The high rate of attrition among clinical-stage therapies, due largely to an inability to predict human toxicity and/or efficacy, underscores the need for in vitro models that better recapitulate in vivo human biology. In much the same way that additive manufacturing has revolutionized the production of solid objects, three-dimensional (3D) bioprinting is enabling the automated production of more architecturally and functionally accurate in vitro tissue culture models. Here, we provide an overview of the most commonly used bioprinting approaches and how they are being used to generate complex in vitro tissues for use in toxicology and disease modeling research.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Toxicología
/
Enfermedad
/
Bioimpresión
/
Impresión Tridimensional
/
Modelos Biológicos
Tipo de estudio:
Prognostic_studies
Límite:
Humans
Idioma:
En
Revista:
Drug Discov Today Technol
Año:
2017
Tipo del documento:
Article
Pais de publicación:
Reino Unido