Your browser doesn't support javascript.
loading
Cytotoxic and genotoxic effects of silver nanoparticle/carboxymethyl cellulose on Allium cepa.
Becaro, Aline A; Siqueira, Maria Célia; Puti, Fernanda C; de Moura, Marcia Regina; Correa, Daniel S; Marconcini, José Manoel; Mattoso, Luiz H C; Ferreira, Marcos David.
Afiliación
  • Becaro AA; Programa de Pós-Graduação em Biotecnologia (PPGBiotec), Centro de Ciências Exatas e Tecnologia, Universidade Federal de São Carlos (UFSCar), São Carlos, SP, 13565-905, Brazil.
  • Siqueira MC; Laboratório Nacional de Nanotecnologia para o Agronegócio (LNNA), EMBRAPA Instrumentação, São Carlos, SP, 13560-970, Brazil.
  • Puti FC; Laboratório Nacional de Nanotecnologia para o Agronegócio (LNNA), EMBRAPA Instrumentação, São Carlos, SP, 13560-970, Brazil.
  • de Moura MR; Programa de Pós-Graduação em Química (PPGQ), Centro de Ciências Exatas e Tecnologia, Universidade Federal de São Carlos (UFSCar), São Carlos, SP, 13565-905, Brazil.
  • Correa DS; Programa de Pós-Graduação em Biotecnologia (PPGBiotec), Centro de Ciências Exatas e Tecnologia, Universidade Federal de São Carlos (UFSCar), São Carlos, SP, 13565-905, Brazil.
  • Marconcini JM; Laboratório Nacional de Nanotecnologia para o Agronegócio (LNNA), EMBRAPA Instrumentação, São Carlos, SP, 13560-970, Brazil.
  • Mattoso LHC; Departamento de Física e Química, UNESP, Ilha Solteira, SP, 15385-000, Brazil.
  • Ferreira MD; Programa de Pós-Graduação em Biotecnologia (PPGBiotec), Centro de Ciências Exatas e Tecnologia, Universidade Federal de São Carlos (UFSCar), São Carlos, SP, 13565-905, Brazil.
Environ Monit Assess ; 189(7): 352, 2017 Jul.
Article en En | MEDLINE | ID: mdl-28646437
Several mutagenic agents may be present in substances released in the environment, which may cause serious environmental impacts. Among these substances, there is a special concern regarding the widespread use of silver nanoparticles (AgNP) in several products due to their widely known bactericidal properties, including in the medical field and the food industry (e.g., active packaging). The assessment of the effects of AgNP released in the environment, having different concentrations, sizes, and being associated or not to other types of materials, including polymers, is therefore essential. In this research, the objective was to evaluate the genotoxic and cytotoxic effects of AgNP (size range between 2 and 8 nm) on root meristematic cells of Allium cepa (A. cepa). Tests were carried out in the presence of colloidal solution of AgNP and AgNP mixed with carboxymethylcellulose (CMC), using distinct concentrations of AgNP. As a result, when compared to control samples, AgNP induced a mitotic index decrease and an increase of chromosomal aberration number for two studied concentrations. When AgNP was in the presence of CMC, no cytotoxic potential was verified, but only the genotoxic potential for AgNP dispersion having concentration of 12.4 ppm.
Asunto(s)
Palabras clave
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Plata / Allium / Carboximetilcelulosa de Sodio / Nanopartículas del Metal Idioma: En Revista: Environ Monit Assess Asunto de la revista: SAUDE AMBIENTAL Año: 2017 Tipo del documento: Article País de afiliación: Brasil Pais de publicación: Países Bajos
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Plata / Allium / Carboximetilcelulosa de Sodio / Nanopartículas del Metal Idioma: En Revista: Environ Monit Assess Asunto de la revista: SAUDE AMBIENTAL Año: 2017 Tipo del documento: Article País de afiliación: Brasil Pais de publicación: Países Bajos